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临床试验/NCT07148167
NCT07148167已完成不适用

Cervical MRI Findings in Patients With Ankylosing Spondylitis

Kayseri City Hospital1 个研究点 分布在 1 个国家目标入组 158 人开始时间: 2025年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
158
试验地点
1
主要终点
servical MRI fındings in AS patients,

研究概览

简要总结

In the literature, we found only one study evaluating the thickness of the cervical paraspinal muscles (multifidus, semispinalis cervicis, semispinalis capitis, splenius capitis, and trapezius) in patients with AS. This study examined the morphology of all neck extensor muscles (multifidus, semispinalis capitis, semispinalis cervicis, splenius capitis, and trapezius muscles) using ultrasound and their relationship to activities of daily living and compared them with a control group. As is well known, the user's experience is crucial in ultrasound. Furthermore, ultrasound cannot accurately assess the deep paravertebral muscles. Therefore, inspired by this study, we decided to use Magnetic Resonance Imaging (MRI) to evaluate the cervical muscle planes in AS patients in more detailed and objective ways. In this study, in addition to cervical muscle volumes in AS patients, we also aimed to evaluate cervical fat infiltration and cervical alignment, which have not been previously evaluated in AS patients.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Other

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •For the study group:
  • •Patients diagnosed with ankylosing spondylitis, aged 18-
  • •Patients who underwent a cervical MRI between January 2020 and September
  • •Control Group Patients aged 18-50 who underwent cervical MRI between January 2020 and September 2023 due to nonspecific neck pain, who did not have an AS diagnosis and whose cervical MRI was reported as normal.

排除标准

  • •Patients over 50 years of age
  • •History of spine surgery;
  • •Presence of pain, numbness, and weakness in the upper extremities
  • •History of cervical injury or neck injury
  • •Presence of tuberculosis, tumor, fracture, infection, instability, cervical myelopathy, cervical disc herniation (protrusion, extrusion) (will be considered cervical bulging)
  • •Presence of cervical radiculopathy
  • •Those with a detectable pathological spinal condition related to neck pain, including spinal deformity; inflammatory or rheumatic diseases other than AS, malignancies, or neurological diseases
  • •A cognitive or psychological disorder

研究组 & 干预措施

Ankylosing Spondylitis group

For the study group:

  • Patients diagnosed with ankylosing spondylitis, aged 18-50.
  • Patients who underwent a cervical MRI between January 2020 and September 2023.

干预措施: Magnetic resonance imaging (Other)

Control Group

Patients aged 18-50 who underwent cervical MRI between January 2020 and September 2023 due to nonspecific neck pain, who did not have an AS diagnosis and whose cervical MRI was reported as normal.

干预措施: Magnetic resonance imaging (Other)

结局指标

主要结局

servical MRI fındings in AS patients,

时间窗: Patients who underwent cervical MRI between January 2020 and September 2023

the cervical muscle planes, cervical muscle volumes in AS patients cervical fat infiltration

次要结局

未报告次要终点

研究者

发起方
Kayseri City Hospital
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Ayse Guc

Medical Doctor

Kayseri City Hospital

研究点 (1)

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