Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 2
- 主要终点
- Accuracy of CO2 Levels
研究概览
简要总结
Four methods are routinely used to monitor CO2 in patients. End tidal CO2 (EtCO2) is monitored through the endotracheal tube during general anesthesia. CO2 is also monitored in other healthcare settings transcutaneously (TCO2), via finger stick capillary CO2 (CapCO2), and arterial blood gas (ABG). The purpose of this study is to perform all four measurements simultaneously during general anesthesia to identify which measure provides the most accurate data with the least amount of patient risk.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Have a confirmed diagnosis of cystic fibrosis (positive sweat chloride value ≥ 60 mEq/L) and/or genotype with two identifiable mutations consistent with CF, accompanied by one or more clinical features consistent with the CF phenotype)
- •Hemodynamically stable undergoing general anesthesia for a scheduled procedure
排除标准
- •Patients not diagnosed with CF
- •CF patients undergoing anesthesia for emergency procedures
研究组 & 干预措施
CF
Cystic fibrosis patients undergoing general anesthesia.
干预措施: End tidal CO2 (EtCO2) (Other)
CF
Cystic fibrosis patients undergoing general anesthesia.
干预措施: Transcutaneous CO2 (TCO2) (Device)
CF
Cystic fibrosis patients undergoing general anesthesia.
干预措施: Capillary CO2 (CapCO2) (Diagnostic Test)
CF
Cystic fibrosis patients undergoing general anesthesia.
干预措施: Arterial blood gas (ABG) (Diagnostic Test)
结局指标
主要结局
Accuracy of CO2 Levels
时间窗: Immediately following induction of anesthesia
Looking at the accuracy of CO2 levels assessed via end tidal CO2 (ETCO2), capillary CO2 (Cap-CO2), and transcutaneous CO2 (TCCO2) compared to arterial blood gas (ABG) which is the gold standard.
次要结局
未报告次要终点
研究者
Anne May
Assistant Professor of Clinical Pediatrics
Nationwide Children's Hospital