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Clinical Trials/IRCT20210607051507N1
IRCT20210607051507N1
Completed
N/A

asal intermittent positive pressure ventilation with nasal cannula vs. Nasal continuous positive airway pressure as respiratory support in the management of Transient Tachypnea of Newborn: A Randomized Control Trial

Tehran University of Medical Sciences0 sites40 target enrollmentTBD

Overview

Phase
N/A
Intervention
Not specified
Conditions
Transient Tachypnea of Newborn.
Sponsor
Tehran University of Medical Sciences
Enrollment
40
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • N eonates with TTN were identified with the criteria of Rawlings and Smith including
  • 1\.beginning of tachypnea within 6?h after birth;
  • 2\. tenacity of tachypnea for at least 12?h;
  • 3\.chest radiograph compatible with TTN
  • 4\. exclusion of other known respiratory disorders and non\-respiratory disorders likely to cause the same features.
  • Clinical features are consist of tachypnea (respiratory rate more than 60\) with or without cyanosis, signs of distress (nasal ?aring, grunting, and retraction).
  • Radiographic signs may include at least one of these; lung hyper in?ation, perihilar congestion or streaking, ?uid ?lled interlobar ?ssure, bilateral in?ltration, pulmonary edema.
  • All of the neonates were born 37 weeks and older.

Exclusion Criteria

  • neonate delivered less than 37 weeks,
  • significant chromosomal abnormalities,
  • meconium aspiration signs, asphyxia,
  • a newborn baby with a metabolic disorder,
  • congenital heart disease (diagnosed with echocardiography),
  • persistent pulmonary hypertension of neonate,
  • RDS, Pneumonia,
  • and requirement of more than 40 percent FiO2\.
  • We excluded neonates who had positive CRP or positive Blood culture
  • or if chest x rays matched with the diagnosis of pneumonia.

Outcomes

Primary Outcomes

Not specified

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