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Prostate cancer Research International: Active Surveillance (PRIAS) MRI study

Recruiting
Conditions
Prostate cancer
prostate carcinoma
10038588
10036958
Registration Number
NL-OMON50734
Lead Sponsor
Erasmus MC, Universitair Medisch Centrum Rotterdam
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
30
Inclusion Criteria

1) Included into the PRIAS study <7 years ago
2) Men should be fit for curative treatment
3) Participants must be willing to attend the follow-up visits
4) Participants must be willing and able to attend follow-up MRIs and targeted
biopsies

Exclusion Criteria

1) Men who cannot or do not want to be irradiated or operated
2) A former therapy for prostate cancer
3) Men with a contraindication for MR

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The main endpoint is the percentage of men upgraded (Gleason score >=7) at<br /><br>inclusion and at repeat biopsies.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secondary endpoints are the therapy free survival rate, number of biopsies<br /><br>performed, biopsy complications, results after deferred radical treatment,<br /><br>development of metastasis and prostate cancer specific mortality.</p><br>
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