Skip to main content
MedPath Trial logoMedPath TrialMedPath Trial Home
Clinical Trials/NCT00912847
NCT00912847CompletedNot Applicable

Validity and Cost-Effectiveness of a New Screening Test for Hepatocellular Carcinoma

Chinese University of Hong Kong0 sites1,018 target enrollmentStarted: October 1997Last updated:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
1,018
Study OverviewStudy DesignEligibility CriteriaInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

The purpose of this study is:

  1. To establish and compare the diagnostic utilities for hepatocellular carcinoma (HCC) screening tests of (a) HS-AFP, (b) AFP + US,(c) AFP alone and (d) US alone (within HBV carriers between age 40 and 70 years);
  2. To establish the cost-effectiveness of the screening tests;
  3. To compare tumor sizes, resection rates, and survival rates up to 18 months between those who were screened by HS-AFP those of a historical control group that was not screened.

Study Design

Study Type
Observational
Time Perspective
Prospective

Eligibility Criteria

Ages
40 Years to 70 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Age between 40 and 70 years
  • •Seropositive for HBsAg
  • •Child's A or B
  • •Life expectancy of more than 2 years

Exclusion Criteria

  • •Non-HBV related cirrhosis
  • •History of malignancy

Investigators

Sponsor Class
Other

Similar Trials

Active, not recruiting
Not Applicable
Implementation of a Clinical Screening and Response System for Cardiac Complications After Noncardiac SurgeryMyocardial InjuryMyocardial InfarctionPerioperative Complication
NCT05859620University Hospital, Basel, Switzerland900
Completed
Not Applicable
Assessing the Feasibility of Screening and Treating Anxiety and Depression in the Bone Marrow Transplant PopulationAnxietyDepression
NCT04025190UNC Lineberger Comprehensive Cancer Center20
Completed
Not Applicable
Harms of Hepatocellular Carcinoma SurveillanceCarcinoma, Hepatocellular
NCT03756051University of Texas Southwestern Medical Center2,871
Completed
Not Applicable
Diagnostic Screening Tests and Potential Biomarkers in Mitochondrial MyopathiesMitochondrial MyopathiesHealthy Controls
NCT03513835Rigshospitalet, Denmark50
Terminated
Not Applicable
International Study of High-Risk Patients for Hepatocellular Carcinoma Using Liquid BiopsyEarly Stage Liver CancerLiver CirrhosisLiver CancerHepatocellular Carcinoma
NCT05342350Johns Hopkins University360