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临床试验/NCT04151797
NCT04151797已完成不适用

Impact of a Mobile Geriatric Team With a Pharmacist on the Optimisation of Prescriptions in Elderly Inpatients

University Hospital, Toulouse1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2019年11月19日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
200
试验地点
1
主要终点
Change from baseline patients' number of potentially inappropriate prescription at the patient discharge after optimization by a mobile geriatric team with pharmacist

研究概览

简要总结

In patients aged 75 years and older, polypathology is frequent and often associated with polypharmacy. This polypharmacy coupled with a lack of proactive elderly care can sometimes lead to hospitalisation. Due to comorbidities and complex problems, management of geriatric patients usually requires a multidisciplinary approach. In Toulouse University Hospital, elderly inpatients can benefit from a geriatric assessment by a Geriatric Mobile Team. Whether this team improve the prescriptions through the advice of a clinical pharmacist has not been demonstrated yet.

详细描述

All participants will be identified via the geriatrician of the mobile geriatric team with the following inclusion criteria: age ≥ 75 years, ≥ 5 medications per day and being hospitalised either in emergency room, short-stay medicine unit or in a surgery department. For each patient, the pharmacist will detect potentially inappropriate prescribing (based on explicit criteria and an implicit approach) and liaise with the geriatrician for drug optimisations. The pharmaceutical advice will be added to the geriatrician's written report, and then addressed to the relevant physician. The implementation of the proposals will be evaluated immediately at the end of hospitalisation, and then reassessed three months later by calling the patient and/or his community pharmacist. A total of 250 patients will be enrolled over a 12 month-period. The evolution of potentially inappropriate prescribing will be assessed and their cost evaluated.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Supportive Care
盲法
None

入排标准

年龄范围
75 Years 至 —(Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patient aged 75 or older
  • •Having 5 medications or more per day
  • •Being hospitalised either in emergency room, short-stay medicine unit or surgery department

排除标准

  • •Patient refuses to participate
  • •Patient already included in another study

研究组 & 干预措施

Medication therapy management

Experimental

Medication therapy management by pharmacist-led medication review

干预措施: Medication therapy management (Other)

结局指标

主要结局

Change from baseline patients' number of potentially inappropriate prescription at the patient discharge after optimization by a mobile geriatric team with pharmacist

时间窗: Month 0 and max Month 2 (At the patient discharge)

number of potentially inappropriate prescribing per patient before (month 0) and after the intervention of the mobile geriatric team (at the patient discharge)

次要结局

  • Change from baseline patients' number of potentially inappropriate prescription at 3 months after optimization by a mobile geriatric team with pharmacist(Month 0, Month 3)
  • Change from baseline patients' number with at least one potentially inappropriate drug at 3 months after optimization by a mobile geriatric team with pharmacist(Month 0, Month 3)
  • Change from baseline ratio of potentially inappropriate drug per patient at 3 months after optimization by a mobile geriatric team with pharmacist(Month 0, Month 3)
  • Change from baseline mean number of medications per patient at 3 months(Month 0, Month 3)
  • realisation of a pharmacist-led medication review in primary care(Month 3)
  • number of falls 3 months after pharmacist-led medication review(Month 3)
  • mortality 3 months after pharmacist-led medication review(Month 3)
  • re-hospitalisation, including emergency room transfers(Month 3)
  • The nursing home transfers(Month 3)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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