The Association Between Religious Origin and Age, and Vitamin B12 and Folic Acid Plasma Levels in Non Jewish Population in Western Galilee

Not Applicable

Completed

• Conditions: Vitamin B12 Deficiency; Folic Acid Deficiency
• Interventions: Other: Blood Sample

• Registration Number: NCT01297361
• Lead Sponsor: Meir Medical Center

Brief Summary

Vitamin B12 deficiency is more widespread in the population than has been assumed so far. Since a deficiency in this vitamin can lead to irreversible neurological damage, early diagnosis is essential. Vitamin B12 is synthesized exclusively in micro-organisms, and in humans it is an essential component in methyl group transfer and cell division. The vitamin is crucially involved in the proliferation, maturation, and regeneration of neural cells. In combination with folic acid, as an enzymatic essential cofactor in the metabolism of homocysteine, vitamin B12 maintains low homocysteine levels. The aim of the present study is to investigate the relationship between religious origin and age, and Vitamin B12 and Folic acid plasma levels in non Jewish population in Western Galilee. The investigators assumption is that the results of the study will contribute to early detection and treatment of Vitamin B12 and Folic acid deficiencies in order to prevent long term complications.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-01-02
• Study Start: 2011-02
• Study First Submitted QC: 2011-02-15
• Study First Posted: 2011-02-16
• Primary Completion: 2011-11
• Status Verified: 2012-03
• Study Completion: 2012-08
• Last Update Submitted: 2013-04-22
• Last Update Posted: 2013-04-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Age:18 and older
• Able to understand and to sign informed consent

Exclusion Criteria

• Gastrointistinal Diseases
• Malignancy
• Psychiatric disorders
• Pregnancy
• Treatment with Vit B12 or Folic acid

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Plasma Vitamin B12 and Folic acid levels	Blood Sample	Blood sample was drawn

Primary Outcome Measures

Name	Time	Method
The number of participants of each religious origin group with Vitamin B12 deficiency	10 months	The association between religious origin (Cristians, Muslims and Druze) and Vitamin B12 plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of these vitamins will be treated accordingly.
The number of participants of each age group with folic acid deficiency	10 months	The association between age groups (18-40, 41-65 and above 65 years old) and folic acid plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of this vitamin will be treated accordingly
The number of participants of each religious origin group with folic acid deficiency	10 months	The association between religious origin (Christians,Muslims and Druze) and folic acid plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of this vitamin will be treated accordingly.
The number of participants of each age group with Vitamin B12 deficiency	10 months	The association between age groups (18-40, 41-65 and above 65 years old) and Vitamin B12 plasma levels will be investigated by one blood analysis taken once at commence of trial (Day 1). Patients found to have low levels of this vitamin will be treated accordingly

Trial Locations

Locations (1)

Clalit health services; 🇮🇱 Kfar Yassif, Israel