Heparin Resistance: Predictors and Outcomes

Not Applicable

Completed

• Conditions: Off Pump Coronary Artery Bypass Surgery

• Registration Number: NCT01044888
• Lead Sponsor: Yonsei University

Brief Summary

The investigators evaluated clinical impact of reduced heparin responsiveness (HRreduced) on the incidence of perioperative myocardial infarction (MI) and restenosis at 6 months after off-pump coronary artery bypass graft surgery (OPCAB) and identified its predictors.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-04
• Primary Completion: 2008-03
• Study Completion: 2008-09
• Study First Submitted: 2010-01-07
• Study First Submitted QC: 2010-01-07
• Study First Posted: 2010-01-08
• Status Verified: 2012-01
• Last Update Submitted: 2012-01-31
• Last Update Posted: 2012-02-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 199

Inclusion Criteria

• enrolling all consecutive patients scheduled for elective isolated multivessel OPCAB between April 2007 and March 2008

Exclusion Criteria

• presence of known preoperative coagulopathy, emergency operation or preoperative use of an intra-aortic balloon pump.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
incidences of postoperative MI and major morbidity	immediate postoperative period

Secondary Outcome Measures

Name	Time	Method
incidences of cardiac morbidities	6 months following surgery
restenosis of graft vessels	6 months following surgery

Trial Locations

Locations (1)

Yonsei University Severance hospital; 🇰🇷 Seoul, Seodaemungu, Korea, Republic of