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A study to evaluate the immunogenicity and safety of smallpox vaccine as vaccination to monkeypox in healthy adults

Phase 1
Conditions
Monkeypox
D045908
Registration Number
JPRN-jRCTs031220171
Lead Sponsor
jiie Mugen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
50
Inclusion Criteria

1) Persons who have given written consent to participate in the research in person.
2) Men and women who are at least 20 year of age at the time consent is obtained
3) Persons who are expected to work for patients with monkeypox in National Center of Global Health and Medicine
4) Persons who have developed neither monkeypox nor smallpox.

Exclusion Criteria

1) Persons with diseases that are clearly abnormalin immune function
2) Persons using corticosteroids or immunosuppressive drugs (cyclosporine, tacrolimus, azathioprine, biological drugs)
3) Persons with an apparent history of anaphylaxiscaused by components of the smallpox vaccine
4) Patients with apparent fever
5) Persons who are obviously suffering from a serious acute disease
6) Those who are obviously pregnant
7) Persons suffering from a spreading skin disease,which may be impaired by immunization.
8) Persons who are in an inappropriate condition to be immunized.
9) Persons who are judged by the principal investigator to be inappropriate for inclusion in the study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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