The Effectiveness and Safety of the Trial of Labor in Full Term Pregnant Women With Cesarean Section After Spontaneous Labor
- Conditions
- Trial of Labor After CesareanSpontaneous LaborVaginal Birth After Cesarean
- Registration Number
- NCT05215041
- Brief Summary
This study is a multi-center, prospective, observational clinical trial study. 510 full-term pregnant women will be enrolled as subjects, and the ratio of eligible subjects in the two groups is 1:1. In the cesarean section group, full term pregnant women with one prior cesarean section after spontaneous labor who are willing to try the trial of labor after cesarean (TOLAC) and in accordance with the criteria according to the 2016 China vaginal birth after cesarean (VBAC) clinical management guidelines will be enrolled and recorded by our homemade registration form of TOLAC. In the non-cesarean section group, pregnant women after 37 weeks of gestation after spontaneous labor but without vaginal labor contraindications will be enrolled. After spontaneous labor for 24h, their final delivery mode will be recorded. In the following 42 days postpartum, their complications and the neonatal outcome will be followed up.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 510
- Volunteers sign the informed consent
- Age: 20-40 years;
- Singleton, a cephalic presentation;
- No contradiction to vaginal delivery; 5.39~42 weeks; 6.Spontaneous labor
Exclusion criteria:
- Konwn contraindication to vaginal delivery or severe complications;
- Multiple gestation;
- Uterine malformation;
- Severe psychiatric disorder;
- Without family's support.
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vignial birth rate 24 hours After spontaneous labor for up tp 24h, the mode of delivery will be konwn and recorded.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
First Affiliated Hospital of Nanjing Medical University
🇨🇳Nanjing, Jiangsu, China
First Affiliated Hospital of Nanjing Medical University🇨🇳Nanjing, Jiangsu, ChinaTang JinhaiContact