NCT04446897已完成1 期
Treatment of Chronic Medium-severe Periodontitis With Mesenchymal Stem Cells Predifferentiated in Osteogenic Direction Immobilised on a Biodegradable Carrier
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2020年8月3日最近更新:
适应症
干预措施
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- number of patients cured
研究概览
简要总结
Treatment of chronic medium-severe periodontitis with mesenchymal stem cells and mesenchymal stem cells predifferentiated in osteogenic direction
详细描述
The bone defect will be filled with a porous membrane based on bone collagen measuring 5x5 mm or more with mesenchymal stem cells and mesenchymal stem cells predifferentiated in osteogenic direction
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 70 Years 至 70 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •chronic medium-severe periodontitis
排除标准
- •pregnancy
- •breast-feeding
- •acute and chronic infectious diseases: HIV, viral hepatitis, tuberculosis
- •mental disorders
研究组 & 干预措施
mesenchymal stem cells
Experimental
standard treatment according to clinical protocols plus mesenchymal stem cells
干预措施: standard treatment (Other)
standard treatment
Active Comparator
standard treatment according to clinical protocols
干预措施: standard treatment (Other)
mesenchymal stem cells
Experimental
standard treatment according to clinical protocols plus mesenchymal stem cells
干预措施: mesenchymal stem cells (Biological)
结局指标
主要结局
number of patients cured
时间窗: 1 month
number of patients cured
次要结局
未报告次要终点
研究者
研究点 (1)
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