NCT04446897已完成1 期
Treatment of Chronic Medium-severe Periodontitis With Mesenchymal Stem Cells Predifferentiated in Osteogenic Direction Immobilised on a Biodegradable Carrier
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2020年8月3日最近更新:
适应症
干预措施
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- number of patients cured
研究概览
简要总结
Treatment of chronic medium-severe periodontitis with mesenchymal stem cells and mesenchymal stem cells predifferentiated in osteogenic direction
详细描述
The bone defect will be filled with a porous membrane based on bone collagen measuring 5x5 mm or more with mesenchymal stem cells and mesenchymal stem cells predifferentiated in osteogenic direction
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 70 Years 至 70 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •chronic medium-severe periodontitis
排除标准
- •pregnancy
- •breast-feeding
- •acute and chronic infectious diseases: HIV, viral hepatitis, tuberculosis
- •mental disorders
研究组 & 干预措施
mesenchymal stem cells
Experimental
standard treatment according to clinical protocols plus mesenchymal stem cells
干预措施: mesenchymal stem cells (Biological)
结局指标
主要结局
number of patients cured
时间窗: 1 month
number of patients cured
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
已完成
1 期
Clinical Trials of Regeneration for Periodontal TissueAdult PeriodontitisNCT00221130Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan10
已完成
早期 1 期
Treatment of gum diseaseChronic periodontitis.Gingivitis and periodontal diseasesIRCT2013110215236N1aser Department, Dental School of Tehran University of Medical Sciences44
尚未招募
不适用
Effect of Internal and External Micro-needling in Treatment of Stage III PeriodontitisPeriodontal DiseasesNCT06578403Misr University for Science and Technology66
已完成
4 期
Clinical and Microbiological Effects of an Essential Oils Solution Used as an Adjunct to Daily Oral Hygiene Practices in Chronic Periodontitis Patients in Supportive CareChronic PeriodontitisNCT01195493University Hospital, Ghent50
终止
不适用
Chronic Periodontitis and Tooth Loss in Patients With Rheumatoid ArthritisRheumatoid ArthritisPeriodontitisNCT02441920University of Birmingham400