Treatment of Chronic Medium-severe Periodontitis With Mesenchymal Stem Cells Predifferentiated in Osteogenic Direction
Phase 1
Completed
- Conditions
- Periodontitis, Chronic
- Interventions
- Biological: mesenchymal stem cellsOther: standard treatment
- Registration Number
- NCT04446897
- Brief Summary
Treatment of chronic medium-severe periodontitis with mesenchymal stem cells and mesenchymal stem cells predifferentiated in osteogenic direction
- Detailed Description
The bone defect will be filled with a porous membrane based on bone collagen measuring 5x5 mm or more with mesenchymal stem cells and mesenchymal stem cells predifferentiated in osteogenic direction
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
- chronic medium-severe periodontitis
Exclusion Criteria
- pregnancy
- breast-feeding
- acute and chronic infectious diseases: HIV, viral hepatitis, tuberculosis
- mental disorders
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description mesenchymal stem cells mesenchymal stem cells standard treatment according to clinical protocols plus mesenchymal stem cells mesenchymal stem cells standard treatment standard treatment according to clinical protocols plus mesenchymal stem cells standard treatment standard treatment standard treatment according to clinical protocols
- Primary Outcome Measures
Name Time Method number of patients cured 1 month number of patients cured
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
🇧🇾Minsk, Belarus