Predictive value of serum microRNA on effect of acupuncture in patients with premature ovarian insufficiency: a nested case-control study
Phase 1
Recruiting
- Conditions
- premature ovarian insufficiency
- Registration Number
- ITMCTR2000004172
- Lead Sponsor
- Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- Not specified
Inclusion Criteria
1) Aged 18-40 years;
2) Meet the diagnostic criteria of POI or in the subclinical stage of POI.
Exclusion Criteria
1) Patients with polycystic ovary syndrome, hyperprolactinemia, hyperandrogenism, hypothyroidism, adrenocortical hypofunction and other endocrine diseases that affect ovulation;
2) Patients with severe cardiovascular and cerebrovascular diseases, nephropathy
,hepatopathy, malignant tumor, hematopoietic diseases and mental disease;
3) Patients who refused to sign informed consent.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method AFC;microRNA;
- Secondary Outcome Measures
Name Time Method clinical pregnancy;basal serum level of FSH, LH and E2;Numbers of retrieved oocytes;AMH;