Comparative study between Ondansetron and Palonosetron in prevention of Postoperative nausea vomiting under general anaesthesia -Double blinded randomised control study.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 134
- 试验地点
- 1
- 主要终点
- Complete response assessed by incidence of nausea ,vomiting and use of rescue anti emetics
研究概览
简要总结
This is a double blind randomised controlled trial to compare the efficacy of Palonosetron and Ondansetron in preventing PONV in patients undergoing general anaesthesia. Primary outcome of the study will be complete response assessed by incidence of nausea, vomiting and use of rescue anti emetics. Secondary outcomes of the study will be to assess patient satisfaction and side effects.This study help us to know which anti emetic is better in preventing post operative nausea and vomiting.The information we get may help us to treat future patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •ASA physical status I, II.
- •Between 18 to 65 yrs. of age.
- •Both genders.
排除标准
- •Patient refusal.
- •Allergic to study drugs.
- •Pregnant women.
- •History of motion sickness, acid peptic disease.
- •Patients on any anti emetics 24hrs prior to surgery.
结局指标
主要结局
Complete response assessed by incidence of nausea ,vomiting and use of rescue anti emetics
时间窗: 1 Year
次要结局
- 1) Patient satisfaction(2) Side effects - headache, dizziness.)
研究者
Dr Lahari priya Vempuluru
Dr Rangarajan Memorial Hospital (Sundaram medical foundation)
