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临床试验/CTRI/2024/04/065741
CTRI/2024/04/065741尚未招募3 期

Comparative study between Ondansetron and Palonosetron in prevention of Postoperative nausea vomiting under general anaesthesia -Double blinded randomised control study.

DR LAHARI PRIYA VEMPULURU1 个研究点 分布在 1 个国家目标入组 134 人开始时间: 2024年4月23日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
134
试验地点
1
主要终点
Complete response assessed by incidence of nausea ,vomiting and use of rescue anti emetics

研究概览

简要总结

This is a double blind randomised controlled trial to compare the efficacy of Palonosetron and Ondansetron in preventing PONV in patients undergoing general anaesthesia. Primary outcome of the study will be complete response assessed by incidence of nausea, vomiting and use of rescue anti emetics. Secondary outcomes of the study will be to assess patient satisfaction and side effects.This study help us to know which anti emetic is better in preventing post operative nausea and vomiting.The information we get may help us to treat future patients.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • ASA physical status I, II.
  • Between 18 to 65 yrs. of age.
  • Both genders.

排除标准

  • Patient refusal.
  • Allergic to study drugs.
  • Pregnant women.
  • History of motion sickness, acid peptic disease.
  • Patients on any anti emetics 24hrs prior to surgery.

结局指标

主要结局

Complete response assessed by incidence of nausea ,vomiting and use of rescue anti emetics

时间窗: 1 Year

次要结局

  • 1) Patient satisfaction(2) Side effects - headache, dizziness.)

研究者

发起方
DR LAHARI PRIYA VEMPULURU
申办方类型
Other [This is post graduate thesis study ]
责任方
Principal Investigator
主要研究者

Dr Lahari priya Vempuluru

Dr Rangarajan Memorial Hospital (Sundaram medical foundation)

研究点 (1)

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