Additive value of platelet rich plasma (PRP) in surgical treatment of stable vitiligo .A randomized double blind comparative study.
Phase 4
- Conditions
- Skin and Connective Tissue Diseases
- Registration Number
- PACTR202108873035929
- Lead Sponsor
- Dr. Dalia Abdel Halim
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Patients with non-segmental stable vitiligo(NSV) with two comparable acral lesions, either symmetrical or in the same anatomical area.
-patients with non acral vitiligo with lesions at elbows, knees or wrists.
-Stability for = 1 year
-Age >12years
- patients not on treatment for at least 1 month prior to surgery.
Exclusion Criteria
Non acral vitiligo in areas other than elbows , knees and wrists .
-Segmental vitiligo.
- Acral vitiligo responsive to conventional treatment modalities
- Active vitiligo; new lesions, expansion of old lesions or koebnerization in < 1 year
- Age < 12 years.
-pregnant and lactating females.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessing the additive value of PRP to NCES by comparing percent improvement in the lesion via point counting and Vitiligo Extent Score for target lesion VESTA Score .
- Secondary Outcome Measures
Name Time Method -Assessing the possible influence of disease duration , the age of the patient , the extent of lesional pigmentation prior to therapy (VESTA) and duration of stability on the outcome of the NCES compared to the PRP enriched NCES in patients with stable vitiligo