Calyx to parenchyma ratio (CPR) in assessing the surgical outcomes in children with pelvi-ureteric junction obstruction undergoing Anderson-Hynes pyeloplasty
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The primary outcome of the study will be to study the trends in the CP ratio in pre-operative and post-operative periods of patients undergoing Anderson Hynes pyeloplasty for PUJ obstruction.
研究概览
简要总结
Pediatric patients diagnosed with pelvi ureteric junction obstruction who are planned for pyeloplasty will be considered for this prospective observational study of 2 years duration. Calyx to parenchyma ratio in the most dilated renal calyx od the affected kdiney will be measured pre op and 6 months post op. These findings will be compared with the more standard imaging tool, i.e., EC scan, to see the surgical outcome in the patients. This will thereby help us to identify whether CP ratio is a significant non invasive marker to prognosticate patients with PUJ obstruciton.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Year(s) 至 18.00 Year(s)（—）
- 性别
- All
入选标准
- •Diagnosed (antenatally/ postnatally) with PUJO with AP diameter of pelvis greater than 1cm on USG and scheduled for Anderson-Hynes pyeloplasty.
- •Informed consent obtained from parents/guardians.
排除标准
- •Previous renal surgery
- •Presence of other significant renal pathologies (e.g., vesico-ureteric reflux, secondary PUJO).
- •Non-compliance with follow-up protocols.
结局指标
主要结局
The primary outcome of the study will be to study the trends in the CP ratio in pre-operative and post-operative periods of patients undergoing Anderson Hynes pyeloplasty for PUJ obstruction.
时间窗: The outcome will be measured at baseline and 6 months following the surgery.
次要结局
- The secondary outcome of the study will be to analyse the usefulness of CP ratio as a non-invasive tool to determine the surgical outcomes in patients with PUJ obstruction(The outcome will be measured at 6 months after surgery)
研究者
Tejaswini Girish
KMC Manipal