Sarcopenia, Obesity, and Resistance Training

Not Applicable

• Conditions: Aging; Obesity; Sarcopenia
• Interventions: Behavioral: Resistance Training

• Registration Number: NCT02681744
• Lead Sponsor: University of Brasilia

Brief Summary

The purpose of this study was to examine the effects of resistance training on sarcopenic obesity in older women.

Detailed Description

To examine the effects of resistance training on sarcopenic obesity in older women, a representative sample of older women from Brasília, Brazil (n\>244 subjects), will be recruited and invited to undergo body composition measurement using dual-energy x-ray absorptiometry. Moreover, the Sarcopenic Obesity index and isokinetic strength evaluations will be performed. It will be a single-blind randomized, controlled 24-week clinical trial, in which experimental group will receive a progressive resistance training program, meanwhile control group will receive instructions to maintain their lifestyle habits. Randomization will be conducted by computer-generated list in blocks of 10. Additionally, body composition, strength assessment, and sarcopenic index will collected and compared after the intervention period.

Study Timeline

• Status Verified: 2016-02
• Study Start: 2016-02
• Study First Submitted: 2016-02-10
• Study First Submitted QC: 2016-02-10
• Last Update Submitted: 2016-02-11
• Study First Posted: 2016-02-12
• Last Update Posted: 2016-02-15
• Primary Completion: 2016-08
• Study Completion: 2016-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 244

Inclusion Criteria

• Community older women (aged between 60 and 80 years).

Exclusion Criteria

• individuals with any metallic implant or artificial pacemaker, who had undergone hip surgery, who were unable to walk without assistance and those affected by metabolic or endocrine disorders that affect the muscular system.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Experimental group	Resistance Training	Participants from the experimental group will assign to the resistance training program undergo physician screening at rest and under cardiopulmonary exercise test conditions before starting the program. Following a three-week familiarization process, participants undergo one repetition maximum (1-RM) testing for each of the exercises of the training program. This procedure intended to determine exercise load and will be systematically repeated in four-week intervals. Volunteers will train thrice per week during 24 weeks. The training program will involve the following exercises: chest press, lat pulldown, knee extension, hamstrings curl, leg press, hip abduction.

Primary Outcome Measures

Name	Time	Method
Laboratorial Body Composition assessment (DXA)	30 minutes	DXA-derived body fat and DXA-derived fat free mass

Secondary Outcome Measures

Name	Time	Method
Isokinetic peak torque of leg extension (dynamometer isokinetic)	20 minutes	Dominant leg extension peak torque will be recorded in three sets of maximal effort

Trial Locations

Locations (1)

Faculdade de Educação Física; 🇧🇷 Brasília, Distrito Federal, Brazil