Efficacy of dexamethasone, IV-IG and Interferone beta for treatment of patients with severe COVID-19

Phase 2

Recruiting

• Conditions: U07.1; COVID-19.; COVID-19, virus identified

• Registration Number: IRCT20120225009124N4
• Lead Sponsor: Gorgan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 April 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

Age 18-70 years
Sever COVID19 disease with the following criteria: SPpO2 below 90% and respiratory rate higher 24 per minute; Involvement of more that 50% of lung in CT-scan

Exclusion Criteria

Need for intubation at the time of admission
Contraindication of corticosteroids, IV IG and interferon beta
Pregnancy, lactation

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in SpO2 (increasing in level of SpO2 to levels higher than 90%). Timepoint: After finishing the intervetion. Method of measurement: By Pulse oximeter.

Secondary Outcome Measures

Name	Time	Method
Duration of stay in hospital. Timepoint: After finishing the intervention. Method of measurement: Reviewing patient hospital file.;Intubation. Timepoint: After finishing the intervention. Method of measurement: Reviewing patient hospital file.;Mortality. Timepoint: After finishing the intervention. Method of measurement: Reviewing patient hospital file.