Effect of targeted carotid cryotherapy on resting cardiovascular parameters in healthy volunteers - A Randomized Controlled Trial
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 114
- 试验地点
- 1
- 主要终点
- Heart Rate Variability (HRV)
研究概览
简要总结
My current study will be over carotid cryotherapy, commonly accomplished with a cold compress or cryo-wrap applied around the neck. When applied to the carotid triangle, this also targets baroreceptor zones, possibly improving baroreceptor sensitivity.
Healthy subjects, between the age of 18 and 30 years will be identified after obtaining a detailed clinical history and by performing standard clinical physical examinations.After selecting the eligible subject’s, recruitment will be done using a computer-generated random number into two groups.
Group A: Carotid Cryotherapy by Neck wrap with ice application to Carotid area – 5 mins
Group B: Plain neck wrap without ice application – 5 mins
Assessment will be done before and after intervention at time intervals at T = 0,1,2
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Healthy volunteers 2 Age: 18 to 30 years 3 Both Male and female participants 4 Subjects not on drugs or medication.
排除标准
- •1 Individuals with acute infectious disease 2 Recent surgery patients 3 Smoking and Alcohol Consumers 4 Individuals with known Cardiovascular and Respiratory Disease 5 Pregnant women • Weak and debilitating individuals.
结局指标
主要结局
Heart Rate Variability (HRV)
时间窗: T = 0 (Baseline) | T = 1 (immediately after the intervention) | T = 2 (30 mins after intervention)
次要结局
- Blood Pressure(T = 0 (Baseline))
研究者
Dr Savya A D
SDM Collee of Naturopathy and Yogic sciences