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Influence of Implants and Locators for Improved Retention

Not Applicable
Terminated
Conditions
Mouth, Edentulous
Interventions
Device: A Locator with retention elements
Device: B Locator without retention elements
Registration Number
NCT02551146
Lead Sponsor
Philipps University Marburg Medical Center
Brief Summary

The aim of this study is to assess the influence of this particular treatment method on the patients' quality of life and masticatory function.

Detailed Description

For this prospective randomized controlled clinical trial patients with edentulous mandibles and tissue supported (full) dentures were treated with 2 dental implants and locators in order to improve prosthesis stability.

The LOCATOR System is comprised of three parts: The LOCATOR implant attachment (LOCATOR abutment), the LOCATOR Male and the LOCATOR Denture Cap. The abutment is inserted directly into the implant using a torque wrench, while the Denture Cap is placed into the base of the overdenture for polymerization using acrylic resin. Custom retention is achieved via LOCATOR Males - small color-coded (according to retention force) plastic inserts - which can be exchanged as needed.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
14
Inclusion Criteria
  • age 45-80 years (male or female)
  • sufficient full dentures in the mandible
  • must be able to clean their teeth on their own
  • edentulous mandible with interforaminal adequate bone for insertion of implants
  • implantation sites free of infections and root fragments
  • no need for treatment of the maxillary teeth
  • Written Informed Consent
Exclusion Criteria
  • systemic diseases
  • mental disability that may affect the participant's ability to properly follow study instructions
  • oral mucosal diseases
  • long-term medication with steroids, bisphosphonates
  • known allergic reactions to dental materials
  • malignant tumor in the head and neck area
  • requirement of any concurrent radiotherapy or chemotherapy or any radiotherapy or chemotherapy within the last 10 years pregnancy or breastfeeding at study entry

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
A Locator with retention elementsA Locator with retention elementsGC Pilier Locator abutment with retention elements: For patients in the experimental group (arm A) the connection of the full dentures to the implants will be achieved by fitting the dentures with GC Pilier Locator abutments with retention elements.
B Locator without retention elementsB Locator without retention elementsGC Pilier Locator abutment without retention elements: For patients with the active comparator (arm B) the full dentures will get Pilier Locator abutments without retention elements and thus no connection to the implants.
Primary Outcome Measures
NameTimeMethod
Quality of life (OHIP-G-49)3 months after randomization

The oral health-related quality of life is assessed by the German version of the Oral Health Impact Profile questionnaire (OHIP-G-49, Locker et al 1993)

Secondary Outcome Measures
NameTimeMethod
Mucosal recessions3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3)

The mucosal recessions at implants will be assessed and the change from baseline will be documented.

width of keratinized gingiva/mucosa3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3)

The width of keratinized gingiva/mucosa will be assessed and the change from baseline will be documented.

Gingival index3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3)

The Gingival index (Loe and Silness 1963) will be assessed and the change from baseline will be documented.

intraoral photo-documentation3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3)

A photo-documentation (intraoral) will be done to assess the changes from baseline.

masticatory function3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3)

Video documentation of chewing a defined bolus. After chewing a defined bolus for 10 seconds comparison of reduction ratio of the bolus is documented by photography and the change from baseline will be documented.

Plaque index3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3)

The Plaque index (Silness and Loe 1964) will be assessed and the change from baseline will be documented.

Probing pocket depth3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3)

The Probing pocket depth with bleeding on probing (6 sites of every tooth and implant) will be assessed and the change from baseline will be documented.

Gingival recessions3 months (T0), 6 months (T1), 9 months (T2), 12 months (T3)

The Gingival recessions at teeth will be assessed and the change from baseline will be documented.

Trial Locations

Locations (1)

Dept. of Prosthodontics and Orofacial Function Philipps-University, School of Dental Medicine

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Marburg, Germany

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