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Efficacy of Tacrolimus ointment in the treatment of tinea versicolor

Phase 2
Conditions
Pityriasis versicolor.
Pityriasis versicolor
Registration Number
IRCT2014021216557N1
Lead Sponsor
Research Council of Shiraz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
50
Inclusion Criteria

Clinical diagnosis of tinea versicolor; Confirmation of diagnosis by Wood's lamp examination (Yellow fluorescence) and Direct smear; Patients of 10 year old and over; Less than 15% of body surface area involvement

Exclusion criteria: Pregnancy or Lactation; History of hypersensitivity to main or preservative ingredients of topical tacrolimus or clotrimazole; Serious skin or systemic diseases; History of consumption of topical or systemic antifungal medications in the recent 1 month before enrolling in study

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Wood's lamp fluorescence. Timepoint: 0, 3rd, and 5th week. Method of measurement: Wood's lamp radiation.;Scale and hyperpigmentation grade. Timepoint: 0, 3rd, and 5th week. Method of measurement: Physician global assessment.;Malassezia species positivity. Timepoint: o, 3rd and 5th weeks. Method of measurement: Direct KOH 10% smear.
Secondary Outcome Measures
NameTimeMethod
Pruritus. Timepoint: 0, 3rd, and 5th week. Method of measurement: Visual assessment scale.;Hypopigmentation. Timepoint: 0, 3rd, and 5th week. Method of measurement: Physician global assessment.
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