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Clinical Trials/NCT05944341
NCT05944341
Recruiting
Not Applicable

Articaine Success in Pulpectomy of Primary Molars With Irreversible Pulpitis in Children Under Four Years: a Randomized Controlled Trial

Minia University1 site in 1 country164 target enrollmentStarted: June 1, 2023Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Sponsor
Minia University
Enrollment
164
Locations
1
Primary Endpoint
Face, Legs, Activity, Cry, Consolability pain scale

Overview

Brief Summary

A two-tailed randomized controlled trial with two parallel arms is aimed to compare success proportions of the articaine and lidocaine groups in children with irreversible pulpitis under 4 years. The participants will be randomly assigned into two equal groups (82 children per group): the control group will receive lidocaine and the intervention group will receive the articaine local anesthesia.

The direct observation tool FLACC was considered to assess pain severity. The behavior was assessed during pulpectomy procedures using the Frankl behavior rating scale (FBRS)

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Other
Masking
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
36 Months to 47 Months (Child)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Healthy 36-47 month-children (ASA class I or II) weighing at least 15 kilograms
  • Children should be intellectually fit, and cooperative, with no behavior or communication abnormalities
  • Presence of a carious maxillary or mandibular second primary molars with signs and symptoms of irreversible pulpitis

Exclusion Criteria

  • Molars with unrestorable crowns
  • Molars with necrotic pulps, pathological mobility, gingival swelling or abscess, fistulous or sinus tract, or apical periodontitis

Outcomes

Primary Outcomes

Face, Legs, Activity, Cry, Consolability pain scale

Time Frame: up to 24 hours

its scores range from None/mild pain scores 0-3 Moderate pain scores 4-6 Severe pain scores 7-10

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Minia University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Ahmad Elheeny

Assistant Professor

Minia University

Study Sites (1)

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