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临床试验/NL-OMON26275
NL-OMON26275尚未招募不适用

Early detection of pulmonary exacerbations in mucociliary clearance diseases: Molecular fingerprinting by exhaled breath and microbiome analysis.

Dept. Respiratory Medicine Academic Medical Centre, University of Amsterdam0 个研究点目标入组 100 人开始时间: 待定最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100

研究概览

简要总结

/A

研究设计

研究类型
Observational

入排标准

入选标准

  • 1. CF diagnosis is based on: clinical symptoms in combination with an abnormal sweat test (chloride > 60 mmol/l) and/or identification of mutations in both alleles of the CFTR gene;
  • 2. PCD diagnosis is based on: A combination of clinical symptoms, abnormal movement of cilia on microscopic evaluation of respiratory epithelial biopsies and epithelial cell cultures, or identification of an ultra structural defect in the cilia by electron microscopy;

排除标准

  • 1. Mental retardation;
  • 2. Diabetes Mellitus (CF complication);

研究者

发起方
Dept. Respiratory Medicine Academic Medical Centre, University of Amsterdam

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