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Flexible Dose, Long-term Safety Study of Asenapine for the Treatmentof Schizophrenia in Adolescents (P05897 AM1) (ADDRESS-97)

Phase 3
Completed
Conditions
Health Condition 1: null- Schizophrenia, Paranoid
Schizophrenia, Disorganized
Schizophrenia, UndifferentiatedHealth Condition 2: F209- Schizophrenia, unspecified
Registration Number
CTRI/2012/02/002403
Lead Sponsor
Merck Sharp and Dohme Corp
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
150
Inclusion Criteria

Each participant must be between 12 and 17 years of age at the time of entry on this study, however, participants in the 8-week trial (P05896) who reach 18 years of age while on P05896 may be enrolled in this extension study provided all other inclusion/exclusion criteria are met.

- Must have completed the 8-week efficacy and safety trial (P05896) and, according to the investigators judgment, would benefit from long-term treatment.

- Must have demonstrated an acceptable degree of compliance with trial medication, visits, and other requirements in the 8-week trial (P05896), in the opinion of the investigator.

Exclusion Criteria

- A female participant must not be pregnant and must not have the intention to become pregnant during the trial.

- A participant must not be at imminent risk of self-harm or harm to others.

- A participant must not currently be under involuntary inpatient commitment.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Safety and tolerability of long-term asenapine treatment in adolescentsTimepoint: Through Week 26, plus a minimum of a 30-day follow up
Secondary Outcome Measures
NameTimeMethod
To Collect exploratory efficacy data of long-term treatment with asenapine in adolescents (12 to 17 years of age) with Schizophrenia <br/ ><br>Timepoint: Through Week 26, plus a minimum of a 30-day <br/ ><br>follow up
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