Influence of PBM on Anaerobic Capacity Under Normoxia and Hypoxia

Not Applicable

Active, not recruiting

• Conditions: Performance; Low Level Laser Therapy; Sport; Photobiomodulation
• Interventions: Device: Photobiomodulation therapy

• Registration Number: NCT05595564
• Lead Sponsor: University of Sao Paulo

Brief Summary

The photobiomodulation (PBM) shows positive results in muscle performance, fatigue reduction, management of blood lactate production, analgesia and in the increase of VO2 maximal, favoring the increase of ATP production and thus the energy metabolism. The association of PBM applied before high-intensity treadmill training shows physiological improvements both in normoxic (Nor) and hypoxic (Hip) conditions. Anaerobic capacity (AC) is the maximum amount of ATP that can be resynthesized by anaerobic metabolism and is an important predictor of high-intensity exercise since an athlete's ability to perform efforts to increase maximal oxygen consumption (VO2max) depends on AL. In view of the above information the main objective of the present research project will be to investigate the effects of PBM on AC under normoxic and hypoxic conditions in amateur runners. To test the effects of exercise training on anaerobic capacity under normoxic and hypoxic conditions, 7 individuals will be randomly submitted to four maximal efforts to exhaustion with intensity corresponding to 110% of VO2max in Hip, Nor, Hip+Ebio and Nor+Ebio conditions. These efforts will be used to estimate the AC, that is, the maximum accumulated deficit of alternative oxygen (MAODRED), from the sum of the energy contribution of the anaerobic and lactic metabolisms.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-31
• Primary Completion: 2022-07-01
• Status Verified: 2022-10
• Study First Submitted: 2022-10-18
• Study First Submitted QC: 2022-10-21
• Last Update Submitted: 2022-10-21
• Study First Posted: 2022-10-27
• Last Update Posted: 2022-10-27
• Study Completion: 2022-12-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: Male
• Target Recruitment: 7

Inclusion Criteria

• healthy individuals
• VO2 maximal equal to or greater than 34 ml/kg.min
• capacity for physical activity according to the PAR-Q questionnaire

Exclusion Criteria

• musculoskeletal injury in the last three months;
• cardiovascular diseases;
• use of anabolic, anti-inflammatory and analgesic drugs 72 hours before the evaluations;
• use of alcohol and illicit drugs during the collection period;

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Hypoxia	Photobiomodulation therapy	Participant developed running activity on a treadmill in hypoxic condition, submitted or not to photobiomodulation therapy.
Normoxia	Photobiomodulation therapy	Participant developed treadmill running activity in normoxic condition, submitted or not to photobiomodulation therapy.

Primary Outcome Measures

Name	Time	Method
Analysis of excess oxygen consumption observed after exercise and blood lactate	1 year	To investigate the effects of photobiomodulation on anaerobic capacity in normoxia and hypoxia conditions in amateur runners

Secondary Outcome Measures

Name	Time	Method
Analysis of V02 max by a single supramaximal effort performed to exhaustion	1 year	To determine the alactic and lactic anaerobic and lactic anaerobic participation during exhaustive effort performed at 120% of VO2max in normoxia, hypoxia and with intervention of photobiomodulation

Trial Locations

Locations (1)

University of Sao Paulo; 🇧🇷 Ribeirao Preto, Sao Paulo, Brazil