Examining biological markers of oxidative stress over time in patients with obstructive sleep apnoea following CPAP treatment withdrawal

The Woolcock Institute of Medical Research, University of Sydney0 个研究点目标入组 15 人开始时间: 2019年5月14日最近更新: 2019年11月25日

试验速览

暂无简介。

•Be greater than 50 years old at time of assessment.
•Be fluent in English.
•Have been previously diagnosed with OSA.
•Be currently undertaking CPAP therapy for more than 3 months with good compliance.
•Be willing to attend appointments at both the Woolcock Institute of Medical Research
•and Brain and Mind Centre.

•Have a suspected dementia or amnestic MCI on Telephone interview for the Cognitive
•Status score of <31
•Have a history of stroke or other neurological disorder
•Have a current neurological or psychiatric condition (e.g. schizophrenia)
•History of cardiac atrial fibrillation
•Have an intellectual disability
•Have a current affective disorder (e.g. depression, anxiety)
•Are a shift-worker
•Have current or future plans for trans-meridian travel during the trial period
•Are currently taking any medications known to affect sleep
•Have any contraindications for MRI scanning (e.g. pacemaker)
•Do no demonstrate OSA symptom relapse (specifically apnoeas/hypoapnoeas)

发起方

The Woolcock Institute of Medical Research, University of Sydney