Decreasing social jetlag with blue-light reducing glasses in the evening compared to blue-LED-light emitting glasses in the morning

Withdrawn

Conditions: sleep deprivation and social jetlag
sleep deprivation and circadian misalignment

Registration Number: NL-OMON41846

Lead Sponsor: Rijksuniversiteit Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Withdrawn

Sex: Not specified

Target Recruitment: 30

Inclusion Criteria

Healthy men and women between 18 and 45 years of age
Social jetlag = difference between mid-sleep on workdays and days off of minimum 2 hours
Written informed consent

Exclusion Criteria

• Sleep disorders, e.g. sleep apnoea, narcolepsy, restless legs, primary insomnia (will be asked in the General Questionnaire, appendix F1a)
• Mood disorder; because of the possibility of depressive mood as co-morbidity in late chronotypes we will exclude depressed participants
• Two or more time zones crossed 1 month before study participation
• Shift-work during 5 years prior to participation
• Recent eye surgery (last year), glaucoma or other eye disease
• History of chronic diseases, and/or use of chronic medication for 3 months or longer before study participation
• Alcohol/drug problems (based on answers to General Questionnaire, appendix F1a)
• The use of photosensitizing medication
• Wearing spectacles already (contact lenses allowed)
• Sleeping with open curtains in the bedroom
• Pregnancy; because sleep (one of our main outcome measurement) can be disturbed during pregnancy

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Sleep timing from sleep diaries (subjective) and rest/activity profiles from<br /><br>actimetry (objective) and endogenous circadian phase of melatonin from saliva<br /><br>samples; the start of the rhythm will be measured: dim light melatonin onset<br /><br>(DLMO). A shift in DLMO is interpreted as a shift in the endogenous circadian<br /><br>pacemaker.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Sleep quality from subjective sleep diaries, light exposure assessed from sleep<br /><br>diaries (subjective) and from actimetry (objective). </p><br>