Pregnancy Rate in Direct Versus Afterload Technique of Embryo Transfer
- Conditions
- IVFFertility IssuesEmbryo Transfer
- Registration Number
- NCT05364528
- Lead Sponsor
- Istituto Clinico Humanitas
- Brief Summary
The primary outcome of the study is to determine if a difference in terms of pregnancy rate exists between direct and afterload embryo transfer (ET) techniques.
The secondary end points include the evaluation of the difficult transfer rates.
- Detailed Description
The study database includes all the single fresh and frozen (G5-G6) blastocyst transfers performed at Humanitas Fertility Centre between 1st January 2016 and 31th December 2021 by using the direct and afterload protocols.
Any blastocysts that underwent preimplantation genetic testing will be excluded from the analysis, as well as embryos derived from gamete donation or those imported from other centers.
Data are gathered using a specific internal web-based database, which allows to organize, store and readily retrieve information about patients and IVF cycle.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 8127
- IVF procedure
- Fresh and frozen single blastocyst transfer
- Any blastocysts that underwent PGS testing
- Embryos derived from gamete donation
- Embryos imported from other centers
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method clinical pregnancy rate 6 years number of pregnancies diagnosed by ultrasonographic visualization of one or more gestational sacs x 100 divided by the number of embryo transfer cycles
- Secondary Outcome Measures
Name Time Method difficult transfer rate 6 years advancement of the outer sheath, multiple attempts, force, required manipulation, use of a stylet or tenaculum, dilatation, use of a different catheter