The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning

Completed

• Conditions: Lead Poisoning

• Registration Number: NCT00374894
• Lead Sponsor: China Medical University, China

Brief Summary

Lead poisoning remains a common disease among children despite successful public health efforts that reduced its prevalence.Our study was designed to test the hypothesis that lead-poisoning children (BLLs:100-440µg/L) who were given DMSA and multi-nutrients would have a greater fall than children of other groups at 12 weeks of follow-up.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-03
• Status Verified: 2004-04
• Study Completion: 2004-08
• Study First Submitted: 2006-09-11
• Study First Submitted QC: 2006-09-11
• Last Update Submitted: 2006-09-11
• Study First Posted: 2006-09-12
• Last Update Posted: 2006-09-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• Initial BLLs 100-440µg/L
• Age 3-6y
• No more than two main residences
• House cleaned (no lead contaminated)
• Normal intake history and physical

Exclusion Criteria

• Chelation in the past 12 weeks
• Concomitant Fe deficiency(ferritin<16ng/ml)
• Hemoglobin<10.5g/dL
• Medications affecting mineral metabolism

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

China Medical University; 🇨🇳 Shenyang, Liaoning, China