Effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) on Pain and Quality of Life in Patients With Cancer Neuropathic Pain. Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Effect of Change of 20 rTMS Sessions on Pain
研究概览
简要总结
The purpose of this study is to evaluate the effectiveness of Repetitive transcranial magnetic stimulation (rTMS) on pain and quality of life in patients with cancer neuropathic pain.
Although there are currently different therapeutic options for neuropathic pain, most are limited or restricted to pharmacotherapy. Transcranial magnetic stimulation (TMS) is a tool recently incorporated into neuroscience in the management of neuropathic cancer pain.
The study will include 10 patients with oncologic neuropathic pain who will receive 20 sessions of rTMS and the effect on pain and quality of life.
详细描述
Neuropathic pain is defined as pain caused by a primary lesion or transient dysfunction of the central or peripheral nervous system. In cancer, it is generated as a consequence of multiple factors such as: direct compression of nerve structures, post-surgical nerve injuries, and nerve injuries secondary to chemotherapy. At least 3.5 million people around the world suffer from this symptom associated with cancer; Of this population, 38% experience pain in all stages and 80% in advanced stages, negatively impacting quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with neuropathic pain of oncological origin
- •Patients of legal age (18 years old)
- •Patients using their cognitive faculties
排除标准
- •Pregnancy
- •History of negative reaction to TMS
- •History of seizure, history of epilepsy stroke, brain surgery and cranial metal implants.
结局指标
主要结局
Effect of Change of 20 rTMS Sessions on Pain
时间窗: Day 1 vs Day 20 vs 1st month follow up and vs 3rd month follow up
Assessment of pain quantify by Visual analogue scale rated from 0-10, where 0 is the least pain and 10 the worst pain
Effect of Change of 20 rTMS Sessions on Pain and Functionality
时间窗: Day 1 vs Day 20 vs 1st month follow up and vs 3th month follow up
Assessment of pain severity and functionality quantify by brief pain inventory from 0-10, where 0 is the least pain and 10 the worst pain
次要结局
- Effect of Change of 20 rTMS Sessions on Quality of Life(Day 1 vs Day 20 vs 1st month follow up and vs 3rd month follow up)
研究者
Catalina Lopera Muñetón
Associate Professor
Fundacion Universitaria Maria Cano