Effect of Elliptical Training on Lipids, Glucose and Insulin Homeostasis in Metabolic Syndrome
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Triglycerides
研究概览
简要总结
The growing prevalence of metabolic syndrome (MetS) in the worldwide is becoming a serious health problem and economic burden. MetS has become a crucial risk factor for the development of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD). The rising rates of CVD and diabetes, which are the two leading causes of death. To prevent the progression of MetS to diabetes and CVD, regular physical activity is required.
Elliptical trainer device is a relatively new modality of exercise and is advertised to be superior to a treadmill because of the low joint impact and the more reasonable costs of an elliptical trainer compared to a treadmill. Additional quantitative research is needed to further evaluate the effectiveness of elliptical trainers and the physiological and perceptual responses to the machine.
详细描述
Forty sedentary MeTS patients (from both sexes) will be randomly divided to group A and group B.
-Group A (Elliptical training group): This group (n=20) will receive aerobic training on an elliptical trainer for 16 weeks (3 sessions per week). The session will start with 5 minutes warming up at 50 % of maximal heart rate (MHR), 20-minute continuous ET at 70% of MHR, 12 minutes (4×3) intervals at 90% of MHR with a 3-minute active recovery at 70% of MHR between intervals, and finally 5-minute cool-down period at 50% of MHR.
Group B: this group will continue their normal daily physical activities without any additional training
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The MeTS subjects who will have three or more of the following criteria: 1) waist circumference more than 102 cm, triglycerides more than 150 mg/dL, 3) blood pressure (BP) more than 130/85 mmHg, 4) high-density lipoprotein (HDL) less than 40 mg/dL, .
- •Exclusion criteria:
- •Renal, pulmonary, cardiac, vascular, respiratory, hepatic, autoimmune disorders.
- •Smoker, addictive, cancer, and alcoholic patients.
- •Lower limb arthritis or any orthopaedic problem will hinder the training.
- •Participation in any type of sport training in the previous 6 months.
- •Pregnant or lactating women.
- •Patients with thyroid gland dysfunction.
排除标准
- 未提供
结局指标
主要结局
Triglycerides
时间窗: It will be measured after 16 weeks of training
Triglycerides is one of lipid profile indicators
high density lipoprotein
时间窗: It will be measured after 16 weeks of training
high density lipoprotein is one of lipid profile indicators
次要结局
- Fasting blood glucose(It will be measured after 16 weeks of training)
- Insulin(It will be measured after 16 weeks of training)
- The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance(It will be measured after 16 weeks of training)
- Waist circumference(It will be measured after 16 weeks of training)
- weight(It will be measured after 16 weeks of training)
- Leg strength test(It will be measured after 16 weeks of training)
- Systolic blood pressure(It will be measured after 16 weeks of training)
- diastolic blood pressure(It will be measured after 16 weeks of training)
- % body fat(It will be measured after 16 weeks of training)
研究者
Ali Mohamed Ali ismail
lecturer of Physical Therapy for Cardiovascular / Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University
Cairo University