Neuroplasticity-oriented Cognitive Intervention in Early Onset and First Admission Schizophrenia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- change from baseline at post-training and at 3-months and at 7-months follow-up in each of the following outcome measures: neuropsychological test performance (MCCCB), GAF, PANSS, MEG event-related potentials (M50), alpha activity
研究概览
简要总结
The purpose of this study is to reveal the specific effects of computer-aided cognitive training on course and rehabilitation in early onset schizophrenia
详细描述
Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease. We examine the beneficial effect of computer-aided training program on course and rehabilitation of young psychotic patients with early onset psychosis. In addition we develop predictors for the course of disorder from neuroimaging data.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 17 Years 至 37 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Early Onset Psychosis
排除标准
- •Chronicity
- •Insufficient German skills
结局指标
主要结局
change from baseline at post-training and at 3-months and at 7-months follow-up in each of the following outcome measures: neuropsychological test performance (MCCCB), GAF, PANSS, MEG event-related potentials (M50), alpha activity
时间窗: baseline, post-training (training duration 4 weeks), 3-month follow-up, 7-month follow-up
次要结局
- change from baseline in GAF score at 3-months and 7-moths follow-up(baseline, 3-months follow-up, 7-months follow-up)
研究者
Prof. Dr. Brigitte Rockstroh
Prof. Dr.
University of Konstanz