NICE - Nutritional Impact on Immunological Maturation During Childhood in Relation to the Environment
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 1,950
- 试验地点
- 1
- 主要终点
- Child cognition as measured by Wechsler Preschool and Primary Scale of Intelligence
研究概览
简要总结
Role of the exposome on allergy, caries, and neurophysiological development in childhood.
详细描述
Role of the exposome and epigenetics on allergy, caries, and neurophysiological development in childhood as studied in a birth cohort of 650 trioses. The exposome includes repeated measures of nutrition, micronutritients, microbiota, toxic agents and the clinical outcomes, diagnoses of allergy, caries and neurophysiological functions/dysfunctions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 6 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Born at Sunderby hospital, Region Norrbotten, during time period 2015-2018
排除标准
- •Parents not able to speak or write Swedish
结局指标
主要结局
Child cognition as measured by Wechsler Preschool and Primary Scale of Intelligence
时间窗: Outcome at four years
Cognitive development will be tested face-to-face with Wechsler Preschool and Primary Scale of Intelligence. Increasing scores means increasing intelligence.
Number of participants with food allergy
时间窗: Outcome at six years
Food allergy
Number of participants with rhino-conjunctivitis
时间窗: Outcome at six years
Rhino-conjunctivitis
Numbers of caries lesions (DeMFS = decayed, enamel included, missed, filled, tooth surfaces, in each child
时间窗: Outcome at four years
Cariesfree individuals have a DeMFS = 0 and increasing scores means increasing degree of caries. Maximum DeMFS = 148, minumum DeMFS = 0.
Number of participants with excema
时间窗: Outcome at six years
Excema
Number of participants with frhino-conjuctivitis
时间窗: Outcome at one year
Rhino-conjunctivitis
Number of participants with asthma
时间窗: Outcome at six years
Asthma
次要结局
未报告次要终点