Skip to main content
Clinical Trials/NCT05263622
NCT05263622
Completed
Not Applicable

Guided Biofilm Therapy for Periodontal Patients Using Two Different Devices: a Split-mouth Randomized Clinical Trial

University of Pavia1 site in 1 country20 target enrollmentMarch 22, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Periodontal Diseases
Sponsor
University of Pavia
Enrollment
20
Locations
1
Primary Endpoint
Change in BOP - Bleeding on Probing (percentage)
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Periodontal patients will be treated with Guided Biofilm Therapy. At the baseline (T0), the following clinical indices will be collected: BoP, BS, CAL, PPD. A plaque disclosing agents will be used to instruct the patients to proper oral hygiene procedures. At this stage, using a split-mouth design, quadrants will be randomized to:

  • Airflow and Scaling and calculus removal with EMS Prophylaxis Master handpiece
  • Airflow and calculus removal with Mectron Combi handpiece

Patients will be visited after 1 month (T1) and 2 months (T2), in which the periodontal indexes will be collected again.

After all the procedures, VAS for pain will be assessed, with Schiff Air Index, comfort (patients), comfort (operator), timing for the procedures (minutes), satisfaction questionnaire (for patients and for the operator), consumption of the powders for the two handpiece.

Detailed Description

Periodontal patients that respond to the inclusion criteria and agree to participate in the study will be treated with Guided Biofilm Therapy. At the baseline (T0), the following clinical indices will be collected: BoP, BS, CAL, PPD. A plaque disclosing agents will be used to instruct the patients to proper oral hygiene procedures. At this stage, using a split-mouth design, quadrants will be randomized to: * Airflow and calculus removal with EMS Prophylaxis Master handpiece * Airflow and calculus removal with Mectron Combi handpiece Patients will be visited after 1 month (T1) and 2 months (T2), in which the periodontal indexes will be collected again. Together with periodontal assessment, VAS for pain will be assessed, with Schiff Air Index, comfort (patients), comfort (operator), timing for the procedures (minutes), satisfaction questionnaire (for patients and for the operator), consumption of the powders for the two handpieces.

Registry
clinicaltrials.gov
Start Date
March 22, 2022
End Date
September 2, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Andrea Scribante

Associate Professor, Principal Investigator

University of Pavia

Eligibility Criteria

Inclusion Criteria

  • professional dental hygiene performed at least 6 months before enrollment
  • periodontal disease: grading A or B and staging I-III

Exclusion Criteria

  • neurologic, psychiatric and mental diseases
  • patients taking antibiotics during the study
  • pregnant and breastfeeding women
  • patients undergoing anticancer treatment
  • patients undergoing anticancer therapy

Outcomes

Primary Outcomes

Change in BOP - Bleeding on Probing (percentage)

Time Frame: Baseline, after 30 and 60 days

Site-specific assessment of the presence or absence of gum bleeding after the insertion of the periodontal probe for the detection of PPD, detected on 4 sites (mesial, distal, vestibular, palatal/lingual).

Change in Schiff Air Index - Dental sensitivity test

Time Frame: Baseline, after 30 and 60 days

Scoring criteria: 0. the subject did not respond to air blasting; 1. the subject responded to air blasting; 2. the subject responded to air blasting and requested discontinuation; 3. the subject responded to air blasting, requested discontinuation and considered the stimulus to be painful.

Change in Bleeding Score (BS - Mombelli et al.)

Time Frame: Baseline, after 30 and 60 days

Scoring criteria: 0: no bleeding 1. isolated visible spots 2. blood forms a confluent red line on the mucosal margin 3. profuse and copious bleeding

Change in CAL - Clinical Attachment Loss

Time Frame: Baseline, after 30 and 60 days

Measurement (in mm) of the position of the gingival margin in relation to the cemento-enamel junction (CEJ).

Total time of usage

Time Frame: Baseline

Total time of usage of the two handpieces.

Satisfactory questionnaire for operator

Time Frame: Baseline

Comfort (from 0 to 10) Timing (from 0 to 10)

Comfort for the operator

Time Frame: Baseline

Evaluation of the comfort of the operator from 0 to 10 during professional procedures.

Satisfactory questionnaire for patients

Time Frame: Baseline

Choice of a score from 0 to 10 for all the following questions: * Is the time for the procedures appropriate? * Is the quantity of droplets adequate? * Dental sensitivity * Pain with the first instrument * Pain with the second instrument * General pain

Change in Probing Pocket Depth (PPD)

Time Frame: Baseline, after 30 and 60 days

Evaluation (in mm) of the depth of the gingival sulcus, through a millimeter periodontal probe; it is detected from the gingival margin to the bottom of the gingival sulcus or periodontal pocket, evaluated at 6 sites.

Study Sites (1)

Loading locations...

Similar Trials