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临床试验/NCT07821164
NCT07821164已完成不适用

Effects of Exercise Snacks Versus Home-Based Resistance Training on Muscle Strength in Older Adults With Possible Sarcopenia: A Randomized Controlled Trial

Ziren Zhao1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年5月13日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60
试验地点
1
主要终点
Handgrip Strength

研究概览

简要总结

This study aims to investigate whether exercise snacks, a time-efficient approach involving short bouts of exercise performed throughout the day, can improve muscle strength in older adults with possible sarcopenia. Participants will be randomly assigned to an exercise snacks group, a home-based resistance training group, or a non-exercise control group. The intervention will last 8 weeks. Muscle strength and physical function will be assessed before and after the intervention.

详细描述

Sarcopenia is a common age-related condition characterized by reduced muscle strength and impaired physical function, which may increase the risk of falls, disability, and loss of independence in older adults. Although resistance training is recommended as an effective strategy for improving muscle function, participation among older adults may be limited by time constraints, accessibility, and adherence challenges.

Exercise snacks are a time-efficient exercise strategy consisting of short bouts of physical activity distributed throughout the day. This approach may reduce exercise barriers and improve adherence among older adults. However, evidence regarding the effects of exercise snacks on muscle strength in older adults with possible sarcopenia remains limited.

This randomized controlled trial investigates the effects of 8 weeks of exercise snacks compared with home-based resistance training and a non-exercise control condition in older adults with possible sarcopenia.

A total of 60 older adults will be randomly assigned to three groups: an exercise snacks group, a home-based resistance training group, or a non-exercise control group. Participants in the exercise snacks group will complete brief exercise sessions distributed throughout the day, while participants in the resistance training group will perform a structured home-based exercise program. The control group will maintain their usual lifestyle.

The primary outcomes include muscle strength and physical function, assessed using handgrip strength, 5-time chair stand test, 30-second chair stand test, and isokinetic knee strength testing. Exercise adherence and adverse events will also be recorded throughout the intervention period.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Community-dwelling older adults aged 60 years or older.
  • Meeting the criteria for possible sarcopenia according to the Asian Working Group for Sarcopenia (AWGS) 2019 consensus.
  • Handgrip strength less than 28 kg for men or less than 18 kg for women.
  • Five-time chair stand test time of 12 seconds or longer.
  • Able to independently complete the exercise protocol and outcome assessments.
  • Provided written informed consent before participation.

排除标准

  • Presence of contraindications to physical activity according to the Physical Activity Readiness Questionnaire (PAR-Q).
  • Participation in regular structured resistance training.
  • Use of medications or treatments likely to substantially affect muscle strength.
  • Participation in other interventional studies within the previous three months.
  • Unable to complete the five-time chair stand test independently.

研究组 & 干预措施

Exercise Snacks Group

Experimental

Participants completed an 8-week exercise snacks intervention consisting of brief exercise sessions distributed throughout the day. The exercise protocol included sit-to-stand, alternating seated knee extension, alternating standing knee flexion, high-knee marching in place, and wall push exercises.

干预措施: Exercise Snacks (Behavioral)

Home-based Resistance Training Group

Active Comparator

Participants completed an 8-week structured home-based resistance training program using the same bodyweight exercise protocol as the exercise snacks group but with a different exercise schedule.

干预措施: Home-based Resistance Training (Behavioral)

No Intervention

No Intervention

Participants maintained their habitual lifestyle during the 8-week intervention period and did not receive any structured exercise program.

结局指标

主要结局

Handgrip Strength

时间窗: Baseline and after 8 weeks of intervention

Handgrip strength was assessed using a hydraulic dynamometer. Participants performed three maximal voluntary contractions with the dominant hand, and the highest peak force was used for analysis.

次要结局

  • Five-Time Chair Stand Test(Baseline and after 8 weeks of intervention)
  • 30-Second Chair Stand Test(Baseline and after 8 weeks of intervention)
  • Isokinetic Knee Peak Torque(Baseline and after 8 weeks of intervention)
  • Exercise Adherence(During the 8-week intervention)

研究者

发起方
Ziren Zhao
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Ziren Zhao

Associate Professor

Chongqing Normal University

研究点 (1)

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