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Clinical Trials/NCT03488407
NCT03488407
Completed
Not Applicable

A Prospective Study to Evaluate Feasibility of Routine Use of Radial Access for Primary Angioplasty and to Assess it in Subgroups With Unfavorable Characteristics

Jubilee Mission Medical College and Research Institute0 sites315 target enrollmentMarch 5, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Primary Angioplasty
Sponsor
Jubilee Mission Medical College and Research Institute
Enrollment
315
Primary Endpoint
Evaluation of radial angioplasty success in whole cohort.
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

Primary percutaneous coronary intervention is the preferred treatment for patients with ST-segment acute coronary syndrome. The radial access is an established approach, associated with a reduction in vascular access related complications after primary percutaneous coronary interventions. The purpose of this study is to examine the baseline characteristics, risk factors, procedural parameters and complications in patients with STEMI taken for primary angioplasty by radial access.

Data of all patients with acute STEMI with primary PCI through radial access is to be evaluated for baseline characteristics and procedural parameters and complications. Patients in the prospective study are followed up till discharge and any in-hospital complication noted.

This was a prospective, observational and descriptive study. Three hundred fifteen consecutive patients with an ST-segment elevation acute myocardial infarction (STEMI) treated with primary angioplasty by radial access, admitted between March 2016 and Feb 2017 were analyzed for their baseline characteristics, risk factors, and procedural parameters, complications and outcomes. High risk sub-groups analysis was also done. High risk groups includes patients with age >75yrs, cardiogenic shock, severe LV systolic dysfunction, acute left ventricular failure, high degree AV block, right ventricular infarction and low BMI. The study is conducted among patients with acute STEMI, considered for primary PCI through radial artery access at operator discretion.

This study analyzed the baseline characteristics of patients which includes clinical history, clinical examination, ECG, 2D ECHO, coronary angiogram to evaluate cardiovascular risk factors.

Registry
clinicaltrials.gov
Start Date
March 5, 2016
End Date
February 28, 2017
Last Updated
8 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Jubilee Mission Medical College and Research Institute
Responsible Party
Principal Investigator
Principal Investigator

Dr Rajesh Sharma

Senior Resident

Jubilee Mission Medical College and Research Institute

Eligibility Criteria

Inclusion Criteria

  • All patients presenting with STEMI and being considered for primary PCI through radial access between March 2016 and Feb 2017.

Exclusion Criteria

  • Patients with ACS other than STEMI
  • All primary PCI in STEMI through femoral access.
  • All radial elective PCI.

Outcomes

Primary Outcomes

Evaluation of radial angioplasty success in whole cohort.

Time Frame: one year

Angioplasty success rate (by TIMI flow grade)

Evaluation of in-hospital complication.

Time Frame: One year

Rate of local complications

Secondary Outcomes

  • High risk v/s non-high risk subgroup analysis(one year)

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