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Management of Asthma in School age Children On Therapy - MASCOT

Phase 1
Active, not recruiting
Conditions
Chronic asthma (paediatric population)
MedDRA version: 9.1 Level: LLT Classification code 10049106 Term: Asthma chronic
MedDRA version: 9.1 Level: LLT Classification code 10049868 Term: Asthma exacerbation prophylaxis
Registration Number
EUCTR2008-000511-16-GB
Lead Sponsor
Keele University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Not Recruiting
Sex
Not specified
Target Recruitment
450
Inclusion Criteria

1.Children with physician diagnosed asthma aged 6 years -14 years, 11months
2.Those requiring frequent short-acting beta2 agonist relief therapy = 7 puffs per week
3.Those with symptoms of asthma (i.e. wheeze, shortness of breath but not cough alone) resulting in:
i.Nocturnal wakening in the last week because of asthma symptoms and/or
ii.Asthma has interfered with usual activities in the last week and/or
iii.Those who have had exacerbations, defined as a short course of oral corticosteroids, an unscheduled GP or A&E Department visit or a hospital admission within the previous 6 months.
4.Fully informed written (proxy) consent and assent, where appropriate

Are the trial subjects under 18? yes
Number of subjects for this age range:
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

1.Children receiving long acting beta2-agonists, leukotriene receptor antagonists, regular theophylline therapy or high dose ICS (>1000micrograms and unlicensed beclometasone dipropionate or equivalent at the discretion of the investigator).
2.Children with other respiratory diseases, cystic fibrosis, cardiac disease or immunological disorders.
3.Non-English speaking

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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