Skip to main content
Clinical Trials/CTRI/2025/04/085720
CTRI/2025/04/085720Not yet recruitingPhase 3

Clinical Evaluation of Indirect Occlusal Veneers made with two different materials- An invivo study

Government Dental College and Hospital1 site in 1 country40 target enrollmentStarted: May 20, 2025Last updated:

Trial Snapshot

Phase
Phase 3
Status
Not yet recruiting
Enrollment
40
Locations
1
Primary Endpoint
Zirconia reinforced lithium silicate will perform better than lithium disilicate

Study Overview

Brief Summary

In modern restorative dentistry, the emphasis has shifted toward minimally invasive approaches to manage tooth wear, particularly on occlusal surfaces, while conserving healthy tooth structure. Biocorrosion, caused by chemical, biological, and electrochemical interactions (e.g., dietary acids, GERD), is now a major contributor to tooth wear alongside abrasion and attrition. These conditions can impair aesthetics, reduce vertical dimension, and compromise oral function and quality of life.

Historically, full-coverage crowns following elective root canals were the standard treatment, but they involve significant tooth reduction and associated complications. In contrast, partial coverage restorations like inlays, onlays, overlays, and occlusal veneers have emerged as conservative, biomechanically favorable alternatives.

Occlusal veneers—also known as tabletop restorations—are especially useful for severe occlusal wear. They preserve enamel and require proper bonding protocols and material selection to ensure long-term success. Among restorative materials:

  • Lithium disilicate ceramics (e.g., IPS e.max Press) offer a balance of strength, esthetics, and reliable bonding.
  • Zirconia-reinforced lithium silicate ceramics (e.g., Celtra Press) provide enhanced strength and crack resistance with good bonding and optical properties.

While promising, most data on material performance come from in vitro studies, and there’s a lack of robust  clinical comparisons. Therefore, this study aims to evaluate the clinical performance, survival and complications of lithium disilicate vs. zirconia-reinforced lithium silicate occlusal veneers in vivo.

Study Design

Study Type
Interventional
Allocation
Coin toss, Lottery, toss of dice, shuffling cards etc
Masking
None

Eligibility Criteria

Ages
18.00 Year(s) to 70.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • (a) Age 18-70 years (b) Optimal oral hygiene.
  • (c) Patients with molar-incisor hypomineralization (d) Patients with attrition, abrasion, erosion and biocorrosion.

Exclusion Criteria

  • (a) Patients with poor oral hygiene (b) Heavy smokers or patients with tobacco chewing (c) Pregnant or lactating women.

Outcomes

Primary Outcomes

Zirconia reinforced lithium silicate will perform better than lithium disilicate

Time Frame: 6 months

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other [Government Dental College and Hospital]
Responsible Party
Principal Investigator
Principal Investigator

Dr Keyur Vala

Government Dental College and Hospital, Ahmedabad

Study Sites (1)

Loading locations...

Similar Trials