A pilot study: do physiotherapy joint and muscle movement techniques improve forced expiratory volume in one second (FEV1) in adults with cystic fibrosis?

Completed

• Conditions: utritional, Metabolic, Endocrine: Cystic fibrosis; Nutritional, Metabolic, Endocrine; Cystic fibrosis

• Registration Number: ISRCTN90285133
• Lead Sponsor: Record Provided by the NHSTCT Register - 2007 Update - Department of Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-09-28
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Added June 2008:

1. Reported postural changes, stiffness, discomfort and/or pain of musculoskeletal origin in the thoracic spine or chest wall
2. Diagnosis of cystic fibrosis (confirmed by genotype or a sweat sodium concentration of >70mmol/l or sweat chloride of >60mmol/l)
3. Sixteen years of age or over
4. Patients in a stable clinical state with lung function at the time of entry that is within 10% of the mean of the last two recordings (separated by at least one month).
5. Forced Expiratory Volume in 1 second (FEV1) =30% predicted at time of entry to the study

Exclusion Criteria

Added June 2008:
1. Evidence of a current respiratory exacerbation (worsening) as defined by Thornton et al. 2004
2. Cor pulmonale (right heart failure)
3. Low bone density (Z score < -3)(WHO Study Group 1994)
4. Previous history of spontaneous fractures
5. Past history of spinal fracture or other known arthopathic (joint) or spinal disease process
6. Currently undergoing musculoskeletal (physiotherapy, chiropractic or osteopathic) treatment
7. Pregnancy
8. Inability to give consent
9. Current enrolment in another research trial

Study & Design

• Study Type: Interventional
• Study Design: Not specified