Optimizing iron suppletion after Roux-en-Y Gastric Bypass

Phase 4

Recruiting

Conditions: anemia
irondeficiency
10022958

Registration Number: NL-OMON41030

Lead Sponsor: Rijnstate Ziekenhuis

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 240

Inclusion Criteria

All patients who underwent a gastric bypass and develop a irondeficiency postoperatively. (ferritin< 20microgram/l) Age between 18 and 65 years.

Exclusion Criteria

iron deficiency preoperative, bloodtransfusios during studyperiod, ironcontaining nutritional supplements except the 'standard' multivitamins after bariatric surgery, decreased renal failure, excessive menstruational blood loss, anemia not caused by irondeficiency, accumulation of iron, hypersensitivity for one of the medicinal products, psychiatric illness, pregnancy

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Part 1:<br /><br><br /><br>Serum ferritin, iron, hemoglobin, transferrin saturation, and transferrin after<br /><br>6, 12 and 52 weeks after administration of ferrous fumarate, Losferron or<br /><br>Ferinjet.<br /><br><br /><br>Part 2:<br /><br><br /><br>Iron values in the blood before and 1,2,3,4,5 and 6 hours after the<br /><br>administration of oral ironreplacement in micrograms / dl. The difference<br /><br>between pre- and postoperative absorptionvalues.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Part 1:<br /><br><br /><br>Evaluate patients' preference of the route of administration : administered<br /><br>orally (ferrous fumarate / Losferron) or intravenously (Ferinject). </p><br>