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Clinical Trials/NCT05237531
NCT05237531
Terminated
Not Applicable

Preop Education and Opioid Use After Hand and Wrist Fracture ORIF: A Randomized Controlled Trial at a County Hospital

Emory University1 site in 1 country5 target enrollmentMarch 15, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Distal Radius Fracture
Sponsor
Emory University
Enrollment
5
Locations
1
Primary Endpoint
Change in total oral morphine equivalents consumed from day of surgery to postoperative day 10
Status
Terminated
Last Updated
2 years ago

Overview

Brief Summary

This study will compare opioid consumption in patients undergoing outpatient surgical fixation of distal radius fractures with and without standardized preoperative education at Grady Memorial Hospital.

Detailed Description

The proposed research aims to study the impact of preoperative education on postoperative pain control after outpatient surgery for traumatic wrist fractures. The impact of preoperative education will be studied through patient questionnaires and by tracking postoperative opioid consumption as well as instances of unscheduled healthcare contact after surgery. The study will be a randomized controlled trial. This study imposes no more than minimal risk to study participants. Loss of privacy and breach of confidentiality are risks of this study. All data will be stored securely on Microsoft One Drive, a password-protected, encrypted database which requires two-factor authorization. The study population will be patients aged 18-99 years who are undergoing outpatient surgical management of distal radius fractures at Grady Memorial Hospital. No vulnerable populations will be included. Contact will be made with potential study participants at their preoperative clinic visit. Written informed consent will be obtained. Data will not be publicly available. Data will be deidentified, and no members of the team will have access to the code that identifies patients. Data will be collected in the plastic surgery clinic, orthopedic surgery clinic, and preoperative area at Grady Memorial Hospital. The total respondent burden will be 30 minutes.

Registry
clinicaltrials.gov
Start Date
March 15, 2022
End Date
June 16, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Paul A Ghareeb, MD

Assistant Professor

Emory University

Eligibility Criteria

Inclusion Criteria

  • Any patient over the age of 18 years with a closed carpal, metacarpal, or distal radius fracture undergoing outpatient surgical management at Grady Memorial Hospital, who is willing to participate and mentally capable to consent.

Exclusion Criteria

  • Patients who are inpatients at the time of surgery. Patients who have concomitant injuries on the same extremity as the carpal, metacarpal, or distal radius fracture. Patients with open fractures. Patients unable to tolerate non-steroidal anti-inflammatory drugs (NSAIDs). Non-English speaking patients will be excluded.
  • Adults who are unable to consent will not be included.
  • Individuals who are not yet adults will not be included.
  • Pregnant women will not be included.
  • Prisoners will not be included.
  • Cognitively impaired individuals or individuals with impaired decision-making capacity will not be included.
  • Individuals who speak English will be included. Individuals who have limited English proficiency but speak Spanish as a primary language will not be eligible for inclusion. Spanish-speaking patients will be excluded because the components of the educational protocol (video, questionnaires, surveys) are not available in Spanish.

Outcomes

Primary Outcomes

Change in total oral morphine equivalents consumed from day of surgery to postoperative day 10

Time Frame: Day of surgery, postoperative day 10

Change in oral morphine equivalents consumed from day of surgery to postoperative day 10 (POD 10). The total amount of morphine equivalents consumed between the 2 study arms will be compared.

Secondary Outcomes

  • Total opioid consumption during the postoperative course(Up to postoperative day 10)
  • Total number of opioid refills in the postoperative period(Up to postoperative day 10)
  • Change in average daily VAS pain scores for early (postoperative day 0-3), middle (postoperative day 4-7), and late (postoperative day 8-10) postoperative period between the two study arms(Baseline, postoperative day 0-3, postoperative day 4-7, postoperative day 8-10)
  • Total number of unscheduled healthcare contact (UHC) up to 30 days after surgery(Up to 30 days after surgery)
  • Type of reason of unscheduled healthcare contact (UHC) up to 30 days after surgery(Up to 30 days after surgery)
  • Change in results of Pain Management quiz after education(Preoperative, day of surgery)
  • Postoperative Satisfaction score with education(Postoperative (up to 2 weeks after surgery))
  • Percentage of participants with adequate postoperative pain control(Postoperative (Up to 2 weeks after surgery))

Study Sites (1)

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