NCT07241195招募中不适用
Study on the Construction of Disease Cohort for Fatty Liver in the Elderly and Its Prevention and Treatment Strategies
The Affiliated Hospital of Hangzhou Normal University1 个研究点 分布在 1 个国家目标入组 20,000 人开始时间: 2026年3月12日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 20,000
- 试验地点
- 1
- 主要终点
- Incidence of liver fibrosis
研究概览
简要总结
To establish a cohort of elderly fatty liver disease based on the community medical examination population. Through the large-scale cohort study, the risk factors affecting fatty liver in the elderly will be explored in depth from the aspects of lifestyle, environment and genetics, the development pattern and mechanism of fatty liver in the elderly will be analysed, and the health risk assessment system and Chinese standard for fatty liver in the elderly covering cardiovascular risk, risk of hepatic fibrosis and risk of sarcopenia will be established, so as to provide the scientific basis for the precise intervention of fatty liver in the elderly in China.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 100 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •① Elderly people aged ≥65 years among permanent residents (living for more than 5 years) in the survey area;
- •Imaging diagnosis (ultrasound or FibroScan/FibroTouch) of fatty liver; -③ Voluntary participation in this study and signing an informed consent form.
排除标准
- •①Major disability, mental illness, major wasting disease, severe cardiac, pulmonary and renal insufficiency;
- •Patients with combined primary liver cancer or other types of cancer; -③Patients who have received liver transplant or other organ transplants.
研究组 & 干预措施
control group
Observation Group
Lifestyle interventions
结局指标
主要结局
Incidence of liver fibrosis
时间窗: 2 years
次要结局
- Incidence of cardiovascular disease(2 years)
- Incidence of sarcopenia(2 years)
研究者
研究点 (1)
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