Randomized Assessment of Rapid Endovascular Treatment in Basilar Artery Occlusion Stroke in 115 Hospital

Not Applicable

• Conditions: Stroke, Acute; Basilar Artery Occlusion
• Interventions: Procedure: Thromboectomy

• Registration Number: NCT04177615
• Lead Sponsor: University of Medicine and Pharmacy at Ho Chi Minh City

Brief Summary

This is a prospective, open lable studies conducted in 115 hospital to compare between thromboectomy and Recombinant Tisue Plasminogen Activator only to evaluate the eficacy and safety of endovascular treatment in basilar artery occlusion stroke patients

Detailed Description

Acute basilar artery thrombosis is associated with a poor prognosis. Prevalence of basilar artery occlusion are not known. Although basilar artery occlusion has been reported in 2 per 1000 autopsy cases, basilar artery thrombosis may, in stroke registries, explain as many as 27% of ischemic strokes occurring in the posterior circulation.Various treatments were tried in groups of patients with vertebrobasilar territory infarction but evidence based was not cleared previous studies. Therefore, we conduct this study to evaluate the eficacy and safety of endovascular treatment in basilar artery occlusion stroke patients

Study Timeline

• Status Verified: 2019-11
• Study Start: 2019-11-19
• Study First Submitted: 2019-11-24
• Study First Submitted QC: 2019-11-24
• Last Update Submitted: 2019-11-24
• Study First Posted: 2019-11-26
• Last Update Posted: 2019-11-26
• Primary Completion: 2020-11-19
• Study Completion: 2020-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 109

Inclusion Criteria

• Patients admit to 115 hospital in 24h of Basilar Artery Occlusion Stroke
• NIHSS > 4 points

Exclusion Criteria

• Patients refuse to participate in studies
• Patients with contraindication of either rTPA or thromboectomy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Thromboectomy and rTPA	Thromboectomy	use thromboectomy and rtpa for patient with basilar artery occlusion stroke in 24 hour

Primary Outcome Measures

Name	Time	Method
Survival rate in patients with Basilar Artery Occlusion Stroke	3 months from admission	Survival rate in patients with Basilar Artery Occlusion Stroke
NIHSS in patients wtih Basilar Artery Occlusion Stroke after 24hour admission	24 hours from admission	NIHSS in patients wtih Basilar Artery Occlusion Stroke after 24hour admission

Secondary Outcome Measures

Name	Time	Method
mRS in patients with Basilar Artery Occlusion Stroke	3 months from admission	mRS in patients with Basilar Artery Occlusion Stroke