A phase II trial of hepatic arterial infusion chemotherapy with cisplatin for advanced hepatocellular carcinoma with portal vein tumor thrombosis

Phase 2

• Conditions: Advanced hepatocellular carcinoma with portal vein tumor thrombosis

• Registration Number: JPRN-UMIN000000488
• Lead Sponsor: Hepatobiliary and Pancreatic Oncology Division, National Cancer Center Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-09-12
• Study Completion: 2008-01-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

Not provided

Exclusion Criteria

1) Prior chemotherapy with cisplatin for hepatocellular carcinoma 2) Prior radiotherapy, transcatheter arterial chemoembolization, and hepatic arterial chemotherapy for portal vein tumor thrombosis of hepatocellular carcinoma 3) Refractory pleural effusion or ascites 4) Distant metastases 5) Allergic reaction to iodine contrast material 6) Severe renal disease 7) Severe heart disease 8) Active infection excluding hepatitis B or C viral infection 9) Active concomitant malignancy 10) Severe mental disorder 11) Severe allergic reaction to drug 12) Pregnant and lactating females; females of childbearing age unless using effective contraception

Study & Design

• Study Type: Interventional
• Study Design: Not specified