Comparing 68Ga-CTR-FAPI and 18F-FDG PET/ CT in Cancer Detection

Completed

• Conditions: Tumors; PET / CT; FDG PET/CT; FAPI

• Registration Number: NCT06945432
• Lead Sponsor: Lanzhou University Second Hospital

Brief Summary

The aim of this study is to compare the diagnostic efficacy of 68Ga-CTR-FAPI PET/CT and 18F-FDG PET/CT in various malignant tumors

Detailed Description

This study recruited malignant tumor patients diagnosed by histopathology and imaging at the Nuclear Medicine Department of Lanzhou University Second Hospital from July 2024 to March 2025. The enrolled patients underwent 68Ga-CTR-FAPI PET/CT and 18F-FDG PET/CT scans within one week.

Study Timeline

• Study Start: 2024-07-01
• Status Verified: 2025-02
• Primary Completion: 2025-03-31
• Study Completion: 2025-04-05
• Study First Submitted: 2025-04-18
• Study First Submitted QC: 2025-04-18
• Last Update Submitted: 2025-04-18
• Study First Posted: 2025-04-25
• Last Update Posted: 2025-04-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

(a) Age ≥ 18 years old; (b) Suspected or newly diagnosed malignant tumors, evaluating the therapeutic effect of the tumor, or discovering recurrence/metastasis; (c) Obtain approval from oncologists and agree to undergo 18F-FDG and 68Ga-CTR-FAPI PET/CT scans within one week.

Exclusion Criteria

(a) Pregnancy or lactation period; (b) Claustrophobia. (c) Serious health problems: such as severe heart, liver and kidney dysfunction, diseases that affect the metabolism or clearance of imaging agents.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Lesion uptake	1 day	Standardized uptake value (SUV)

Trial Locations

Locations (1)

The Second Hospital of Lanzhou University; 🇨🇳 Lanzhou, Gansu, China