Efficacy of Low Level Laser Therapy for management of oral ulcers in carcinoma oral cavity patient receiving radiation.
Phase 3
- Conditions
- Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
- Registration Number
- CTRI/2024/03/063583
- Lead Sponsor
- AIIMS Raipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with histologically proven squamous cell carcinoma of oral cavity undergoing radiotherapy in radical or adjuvant setting.
RTOG grade 2 oral mucositis
Performance status (KPS score) = 70
Adequate mouth opening (Inter incisor distance = 3 cm
Exclusion Criteria
Patients who had already received Neoadjuvant chemotherapy
Patient being treated with palliative intent
Patients with distant metastasis
Patients with history of radiotherapy to same site
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patients being treated with laser therapy will have less progression to grade 3 and grade 4 oral mucositis during the treatment durationTimepoint: Baseline, 1st week, 2nd week, 3rd week, 4th week, 5th week, 6th week, 7th week of treatment. <br/ ><br>1 month, 2 month, 3 month after completion of treatment <br/ ><br>
- Secondary Outcome Measures
Name Time Method The number of interruptions will be less in the study group with laser therapy than in <br/ ><br>the control group.Timepoint: Baseline, 1st week, 2nd week, 3rd week, 4th week, 5th week, 6th week, 7th week of treatment