Topical Amethocaine versus Topical Eutectic Mixture of Local Anaesthetic (EMLA)
Phase 4
Not yet recruiting
- Conditions
- Intravenous cannulation in childrenAnaesthesiology - Anaesthetics
- Registration Number
- ACTRN12606000409572
- Lead Sponsor
- Auckland District Health Board
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- All
- Target Recruitment
- 660
Inclusion Criteria
All children having topical anaesthetic applied for intravenous cannulation in our department are eligible.
Exclusion Criteria
Those needing emergency IV access or contraindications to topical anaesthetic (currently <3 months of age or on met-Haemaglobinaemia inducing medicines).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method First attempt cannulation success while in the treatment room. Cannula that are successfully inserted but fall out after the child has left the room are counted as successful cannulation.[]
- Secondary Outcome Measures
Name Time Method Pain [Immediately before,during cannulation and after cannulation.];Cost[]
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie Amethocaine's analgesic effects in pediatric IV cannulation?
How does 4% Amethocaine compare to 5% EMLA in terms of onset time and duration of action for pediatric pain management?
Are there specific biomarkers that predict better response to topical anesthetics like Amethocaine or EMLA in children?
What are the potential adverse events associated with 4% Amethocaine versus 5% EMLA in pediatric emergency settings?
What combination approaches with other anesthetic agents could enhance IV cannulation success in children compared to standalone Amethocaine or EMLA?