Prevalence of Cachexia in Patients Undergoing Chemotherapy

Completed

• Conditions: Cachexia; Cancer

• Registration Number: NCT01939340
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

Cachexia and low nutritional intake are a common phenomena in cancer patients undergoing chemotherapy. The purpose of this study is to assess prevalence of cachexia and low nutritional intake and the impact on quality of life, fatigue and mortality in patients undergoing chemotherapy. Furthermore interactions between these parameters, tumor disease and chemotherapy, respectively.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-04
• Primary Completion: 2012-09
• Study Completion: 2013-05
• Status Verified: 2013-09
• Study First Submitted: 2013-09-06
• Study First Submitted QC: 2013-09-06
• Study First Posted: 2013-09-11
• Last Update Submitted: 2013-09-11
• Last Update Posted: 2013-09-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 285

Inclusion Criteria

• Patients undergoing chemotherapy at least in the second cycle.
• Patients who have signed a written Informed Consent.

Exclusion Criteria

• Patients with implanted pacemaker or defibrillator.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Nutritional intake	1 day	Nutritional intake will be assessed by 24h-recall, which will be analysed with regard to macronutritients

Secondary Outcome Measures

Name	Time	Method
Mortality	6 months	Mortality will be assesses via telephone or consultation of the local death register
Quality of life and fatigue	1 day	EORTC QLQ C-30 will be used to assess quality of life and additionally cancer-related fatigue will be evaluated using Brief Fatigue Inventory.
Cachexia	1 day	Cachexia will be evaluated using the patient-generated Subjective Global Assessment.

Trial Locations

Locations (1)

Dept. of Gastroenterology, Infectiology and Rheumatology (including workspace nutrition medicine), Charité Universitätsmedizin Berlin; 🇩🇪 Berlin, Germany