Effect of Pneumoperitoneum on Remifentanil Requirements in the Surgical Pleth Index-guided Analgesia

Not Applicable

Completed

• Conditions: Gastric Cancer
• Interventions: Other: High end-tidal CO2; Other: Low CO2 group

• Registration Number: NCT03788447
• Lead Sponsor: Ajou University School of Medicine

Brief Summary

The primary purpose of this study is to investigate the effect of pneumoperitoneum on remifentanil requirements in the surgical pleth index-guided analgesia for laparoscopic gastrectomy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-12-24
• Study First Submitted QC: 2018-12-25
• Study First Posted: 2018-12-27
• Study Start: 2019-06-04
• Primary Completion: 2019-09-05
• Study Completion: 2019-09-05
• Status Verified: 2021-01
• Last Update Submitted: 2021-01-06
• Last Update Posted: 2021-01-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 74

Inclusion Criteria

• laparoscopic gastrectomy under general anesthesia

Exclusion Criteria

• atypical hemoglobin disease, infective state, cardiovascular disease, peripheral vascular disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
High CO2 group	High end-tidal CO2	end tidal CO2 : 40-45 mmHg
Low CO2 group	Low CO2 group	end tidal CO2 : 30-35 mmHg

Primary Outcome Measures

Name	Time	Method
total dose of remifentanil	through study completion, an average of 2 hours	total dose of remifentanil to maintain for surgical pleth index \< 50

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine; 🇰🇷 Suwon, Seoul, Korea, Republic of