MEG dementia study

Phase 2

• Conditions: cognitively unimpaired, mild cognitive impairment/dementia due to Alzheime's disease; D000544

• Registration Number: JPRN-jRCTs042220078
• Lead Sponsor: Ono Kenjiro

Brief Summary

Because of lack of research fundings, we could not continue the research, and decide to abort the research programs. There were no participants, therefore, we could not get any data.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-10-20
• Study Completion: 2023-07-13
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 0

Inclusion Criteria

Primary registration
[I] A full medical checkup examinee
[II] Patients with MCI due to AD at Kanazawa university hospital
[III] Patients with AD dementia at Kanazawa university hospital

Secondary registration
[IV] Cognitively unimpaired [CU] group
[V] AD-MCI group
[VI] AD group

[I] A full medical checkup examinee
[i] Age greater than 65 years
[ii] Individuals who have a full medical checkup at Kanazawa Advanced Medical Center
[iii] Written informed consent was obtained from the participant

[II] Patients with MCI due to AD at Kanazawa university hospital
[i] Age greater than 65 years
[ii] Diagnosis of probable mild cognitive impairment [MCI] due to Alzheimer's disease [AD] with high evidence of the pathophysiological process, according to the criteria of the National Institute on Aging Alzheimer's Association Workgroup [NIAAA].
[iii] Written informed consent ans assent were obtained from the legal representative and the patient, respectively.

[III] Patients with AD dementia at Kanazawa university hospital
[i] Age greater than 65 years
[ii] Diagnosis of probable AD dementia with high evidence of the pathophysiological process, according to the criteria of the National Institute on Aging Alzheimer's Association Workgroup [NIAAA].
[iii] Written informed consent ans assent were obtained from the legal representative and the patient, respectively.

[IV] Cognitively unimpaired [CU] group
[i] A full medical checkup examinee at the primary registration
[ii] Diagnosed as cognitive unimpaired by the investigators

[V] AD-MCI group
[i] Out patients of Kanazawa university hospital at the primary registration
[ii] Diagnosed as MCI due to AD by the investigators

[VI] AD group
[i] Out patients of Kanazawa university hospital at the primary registration
[ii] Diagnosed as AD dementia by the investigators

Exclusion Criteria

Primary registration
[I] A full medical checkup examinee
[II] Patients with MCI due to AD at Kanazawa university hospital
[III] Patients with AD dementia at Kanazawa university hospital

Secondary registration
[IV] Cognitively unimpaired [CU] group
[V] AD-MCI group
[VI] AD group

[I] A full medical checkup examinee
[i] Individuals who is unable to take an MRI scan, such as a claustrophobia or having any kind of metal in the body
[ii] Assessed as inappropriate to join the clinical trial by the investigator

[II] Patients with MCI due to AD at Kanazawa university hospital
[i] Individuals who is unable to take an MRI scan, such as a claustrophobia or having any kind of metal in the body
[ii] Assessed as inappropriate to join the clinical trial by the investigator

[III] Patients with AD dementia at Kanazawa university hospital
[i] Individuals who is unable to take an MRI scan, such as a claustrophobia or having any kind of metal in the body
[ii] Assessed as inappropriate to join the clinical trial by the investigator

[IV] Cognitively unimpaired [CU] group
[i] Assessed as inappropriate by the investigator

[V] AD-MCI group
[i] Individuals who have a full medical checkup at Kanazawa Advanced Medical Center
[ii] Assessed as inappropriate by the investigator

[VI] AD group
[i] Individuals who have a full medical checkup at Kanazawa Advanced Medical Center
[ii] Assessed as inappropriate by the investigator

Study & Design

• Study Type: Observational
• Study Design: Not specified